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科研机构
上海药物研究所 [22]
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期刊论文 [21]
会议论文 [1]
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2021 [1]
2019 [2]
2018 [2]
2017 [2]
2016 [2]
2015 [2]
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Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:
Yu, Yang
;
Wu, Shifei
;
Zhang, Jianqing
;
Li, Jiayuan
;
Yao, Changliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/04
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
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  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes (FXRPD)-P-high-L1(low) NSCLC to Anti-PD-1 Immunotherapy
期刊论文
CANCER IMMUNOLOGY RESEARCH, 2019, 卷号: 7, 期号: 6, 页码: 990-1000
作者:
You, Wenjie
;
Li, Lijun
;
Sun, Deqiao
;
Liu, Xueqing
;
Xia, Zongjun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 11, 页码: 1064-1074
作者:
Yang, Qian-Hao
;
Jiang, Cheng-Shi
;
Jin, Tao
;
Xu, Jin-Fang
;
Qu, Ting-Li
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  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
Tetrandrine derivatives
non-small cell lung carcinoma
NSCLC A549 cells
anticancer activities
Suzuki-Miyaura reaction
Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762
作者:
Ai, Jing
;
Chen, Yi
;
Peng, Xia
;
Ji, Yinchun
;
Xi, Yong
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth
期刊论文
PLOS GENETICS, 2017, 卷号: 13, 期号: 7
作者:
Pu, Mengfan
;
Li, Chenggang
;
Qi, Xinming
;
Chen, Jing
;
Wang, Yizheng
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  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 110-119
作者:
Li, Cheng-gang
;
Pu, Meng-fan
;
Li, Chun-zhu
;
Gao, Man
;
Liu, Ming-xia
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
miR-1304
NSCLC
heme oxygenase-1
hemin
Safety, pharmacokinetics, and antitumor properties of anlotinib, an oral multi-target tyrosine kinase inhibitor, in patients with advanced refractory solid tumors
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2016, 卷号: 9
作者:
Sun, Yongkun
;
Niu, Wei
;
Du, Feng
;
Du, Chunxia
;
Li, Shuting
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Anlotinib
Anti-angiogenesis
Phase I study
Advanced refractory solid tumors
Pharmacokinetics
Safety
Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680
作者:
Xiao, Qiang
;
Qu, Rong
;
Gao, Dingding
;
Yan, Qi
;
Tong, Linjiang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
5-(Methylthio)pyrimidine derivatives
Mutant selective inhibitors
Epidermal growth factor inhibitor
NSCLC
Structure-based drug design
Simultaneous determination of gypenoside LVI, gypenoside XLVI, 2 alpha-OH-protopanaxadiol and their two metabolites in rat plasma by LC MS/MS and its application to pharmacokinetic studies
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 1005, 页码: 9-16
作者:
Zhang, Lihua
;
Lin, Yunfei
;
Guan, Huashi
;
Hu, Lihong
;
Pan, Guoyu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Gypenoside
2 alpha-OH-Protopanaxadiol
Gynostemma pentaphyllum
Validation
Pharmacokinetic
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