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科研机构
上海药物研究所 [36]
内容类型
期刊论文 [36]
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2021 [1]
2020 [8]
2019 [2]
2018 [1]
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2016 [5]
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Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes
期刊论文
NATURE METHODS, 2021, 页码: 29
作者:
Xu, Chunlong
;
Zhou, Yingsi
;
Xiao, Qingquan
;
He, Bingbing
;
Geng, Guannan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/06/11
MSpectraAI: a powerful platform for deciphering proteome profiling of multi-tumor mass spectrometry data by using deep neural networks
期刊论文
BMC BIOINFORMATICS, 2020, 卷号: 21, 期号: 1, 页码: 15
作者:
Wang, Shisheng
;
Zhu, Hongwen
;
Zhou, Hu
;
Cheng, Jingqiu
;
Yang, Hao
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
Raw mass spectrometry data
Proteome profiling
Feature swath extraction
Deep neural networks
Multi-tumor types
Leave-one-out cross prediction strategy
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Whole-genome sequence of Phellinus gilvus (mulberry Sanghuang) reveals its unique medicinal values
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2020, 卷号: 24, 页码: 325-335
作者:
Huo, Jinxi
;
Zhong, Shi
;
Du, Xin
;
Cao, Yinglong
;
Wang, Wenqiong
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
Anti-carcinogenesis activity
Genome sequencing
HR-ESI-MS
Inoscavin A
Phellinus gilvus
Phenylpropanoids biosynthesis
Medulloblastoma: Molecular understanding, treatment evolution, and new developments
期刊论文
PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13
作者:
Liu, Xiaohua
;
Ding, Chunyong
;
Tan, Wenfu
;
Zhang, Ao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Medulloblastoma
Pediatric brain tumor
Oncogenic driver gene
Hedgehog pathway inhibitor
Smoothened receptor antagonist
Highly selective monitoring of in-source fragmentation sapogenin product ions in positive mode enabling group-target ginsenosides profiling and simultaneous identification of seven Panax herbal medicines
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2020, 卷号: 1618, 页码: 11
作者:
Zhang, Chun-xia
;
Wang, Xiao-yan
;
Lin, Zhao-zhou
;
Wang, Hong-da
;
Qian, Yue-xin
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
In-source fragmentation
Ginsenoside
Selective ion monitoring
Characteristic chromatogram
Panax
Traditional Chinese medicine formula
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 4, 页码: 17
作者:
Li, Heng
;
Feng, Chunlan
;
Fan, Chen
;
Yang, Yang
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 22, 页码: 10078-10091
作者:
Dalangood, Sumiya
;
Zhu, Zhen
;
Ma, Zhihui
;
Li, Jiaxuan
;
Zeng, Qinghe
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
glycogene
ST3GAL6
urinary bladder cancer
clinical outcome
invasion
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
期刊论文
CELL, 2019, 卷号: 179, 期号: 2, 页码: 561-+
作者:
Gao, Qiang
;
Zhu, Hongwen
;
Dong, Liangqing
;
Shi, Weiwei
;
Chen, Ran
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
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