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CORC

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The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:  Li, Xinzhi;  Yuan, Bingchuan;  Lu, Min;  Wang, Yuqin;  Ding, Na
收藏  |  浏览/下载：37/0  |  提交时间：2022/01/18
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：74/0  |  提交时间：2021/08/17
DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation 期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:  Shuai, Lin;  Li, Bo-Han;  Jiang, Hao-Wen;  Yang, Lin;  Li, Jia
收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17
Allosteric Modulation: Dynamics is Double-"E"dged 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3694-3696
作者:  Xiong, Bing
收藏  |  浏览/下载：15/0  |  提交时间：2021/06/11
Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity 期刊论文
MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177
作者:  Chen, Zhong-Guo;  Wang, Yu-Jun;  Chen, Ruo-Song;  Geng, Fan;  Gan, Chen-Ling
收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：129/0  |  提交时间：2021/05/24
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:  Liu, Na;  Yang, Rui;  Shi, Ying;  Chen, Ling;  Liu, Yating
收藏  |  浏览/下载：33/0  |  提交时间：2020/12/21
The nucleosomal acidic patch helps anchor of de novo DNA methyltransferase DNMT3A2/3B3 complex 期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 16, 页码: 2
作者:  Xu, Ting-Hai;  Liu, Minmin;  Zhou, Edward;  Liang, Gangning;  Xu, Eric H.
收藏  |  浏览/下载：3/0  |  提交时间：2021/05/24

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