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科研机构
上海药物研究所 [36]
内容类型
期刊论文 [36]
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2021 [6]
2020 [2]
2019 [2]
2018 [6]
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2016 [5]
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The double faced role of xanthine oxidoreductase in cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Chen, Man-Man
;
Meng, Ling-Hua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/04
xanthine oxidoreductase (XOR)
ROS
uric acid
cancer therapy
Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:
Yin, Jianpeng
;
Zhan, Desheng
;
Ma, Hui
;
Liu, Huanan
;
Yu, Lifang
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/12/16
YLF466D
AMPK activator
glucose metabolism
lipid metabolism
MIRI
domino reaction
C-H activation
Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
;
Wang, Yun
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2020/07/01
Metabolic characterization of diabetic retinopathy: An H-1-NMR-based metabolomic approach using human aqueous humor
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 414-421
作者:
Jin, Huiyi
;
Zhu, Bijun
;
Liu, Xia
;
Jin, Jing
;
Zou, Haidong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Metabolomics
NMR analysis
Aqueous humor
Diabetic retinopathy
Metabolite-metabolite correlation
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