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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
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2021 [2]
2020 [1]
2019 [1]
2016 [1]
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2014 [2]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Pyrrolidinyl Synthetic Cathinones alpha-PHP and 4F-alpha-PVP Metabolite Profiling Using Human Hepatocyte Incubations
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 1, 页码: 17
作者:
Carlier, Jeremy
;
Diao, Xingxing
;
Giorgetti, Raffaele
;
Busardo, Francesco P.
;
Huestis, Marilyn A.
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  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
alpha-PHP
PV7
4F-alpha-PVP
novel psychoactive substance
synthetic cathinone
bath salt
hepatocyte metabolism
liquid chromatography-high resolution tandem mass spectrometry
Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 卷号: 34, 期号: 3, 页码: 13
作者:
Chen, Zhendong
;
Gao, Yuxiong
;
Zhong, Dafang
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  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
chromatographic methods
clean-up efficiency
derivatization
high-resolution chromatography
recovery
sensitivity
A high-efficiency strategy integrating offline two-dimensional separation and data post-processing with dereplication: Characterization of bufadienolides in Venenum Bufonis as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1603, 页码: 179-189
作者:
Wei, Wenlong
;
Hou, Jinjun
;
Yao, Changliang
;
Bi, Qirui
;
Wang, Xia
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  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Offline two-dimensional liquid
chromatography
GNPS
High-efficiency
Dereplication
Bufadienolides of Venenum Bufonis
Development of Online pH Gradient-Eluted Strong Cation Exchange Nanoelectrospray-Tandem Mass Spectrometry for Proteomic Analysis Facilitating Basic and Histidine-Containing Peptides Identification
期刊论文
ANALYTICAL CHEMISTRY, 2016, 卷号: 88, 期号: 1, 页码: 583-591
作者:
Xu, Jingjing
;
Gao, Jing
;
Yu, Chengli
;
He, Han
;
Yang, Yiming
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Methylhexanamine is not detectable in Pelargonium or Geranium species and their essential oils: A multi-centre investigation
期刊论文
DRUG TESTING AND ANALYSIS, 2015, 卷号: 7, 期号: 7, 页码: 645-654
作者:
ElSohly, Mahmoud A.
;
Gul, Waseem
;
Tolbert, Candice
;
ElSohly, Kareem M.
;
Murphy, Timothy P.
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
MHA
Pelargonium species
Geranium species
Fragmentation patterns study of iridoid glycosides in Fructus Gardeniae by HPLC-Q/TOF-MS/MS
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2014, 卷号: 28, 期号: 12, 页码: 1795-1807
作者:
Fu, Zhiwen
;
Xue, Rui
;
Li, Zhixiong
;
Chen, Mingcang
;
Sun, Zhaolin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Fragmentation patterns
iridoid glycosides
Fructus Gardeniae
HPLC-Q
TOF-MS
MS
Enantioselective HPLC determination and pharmacokinetic study of secnidazole enantiomers in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 卷号: 965, 页码: 224-230
作者:
Du, Jiangbo
;
Zhang, Yifan
;
Chen, Yao
;
Liu, Dongqin
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Secnidazole
Enantiomers
Enantioselective high-performance liquid chromatography
Pharmacokinetics
Applications of Liquid Chromatography-Tandem Mass Spectrometry to Detection and Characterization of Reactive Metabolites
期刊论文
Journal of Chinese Mass Spectrometry Society, 2011, 卷号: 32, 期号: 1, 页码: 1-12
作者:
Xie Cen
;
Zhong Dafang
;
Chen Xiaoyan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
liquid chromatography-tandem mass spectrometry(LC-MS/MS)
reactive metabolites
trapping agents
Identification of metabolites of adonifoline, a hepatotoxic pyrrolizidine alkaloid, by liquid chromatography/tandem and high-resolution mass spectrometry
期刊论文
Rapid communications in mass spectrometry : RCM, 2009, 卷号: 23, 期号: 24, 页码: 3907-16
作者:
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
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