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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [14]
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2021 [1]
2019 [4]
2018 [2]
2017 [3]
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2013 [1]
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Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells
期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 3, 页码: 1057-1069
作者:
Liu, Yuwei
;
Xue, Mengzhu
;
Cao, Danyan
;
Qin, Lihuai
;
Wang, Ying
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/17
Multi-omics
BET inhibitor responses
WNT pathway
Liver cancer
Precise therapy
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
期刊论文
CELL, 2019, 卷号: 179, 期号: 2, 页码: 561-+
作者:
Gao, Qiang
;
Zhu, Hongwen
;
Dong, Liangqing
;
Shi, Weiwei
;
Chen, Ran
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial
期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 期号: 17, 页码: 5212-5220
作者:
Li, Qiao
;
Guan, Xiuwen
;
Chen, Shanshan
;
Yi, Zongbi
;
Lan, Bo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19, 期号: 1, 页码: 12
作者:
Qin, Wenyan
;
Wang, Xiaodong
;
Wang, Yilin
;
Li, Yalun
;
Chen, Qiuchen
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
H19
Genetic polymorphisms
Susceptibility
Colorectal cancer
Prognosis
Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 7, 页码: 1540-1553
作者:
Song, Mengqiu
;
Liu, Xuejiao
;
Liu, Kangdong
;
Zhao, Ran
;
Huang, Hai
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer
期刊论文
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:
Liu, Xue-ling
;
Xu, Yi-chao
;
Wang, Yu-xiang
;
Chen, Yi
;
Wang, Bo-bo
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  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
PIK3CA
HER2
Akt
Patient-derived xenograft (PDX)
Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 35, 页码: 59086-59102
作者:
Zhang, Xuesai
;
Li, Qingrou
;
Zhao, Hui
;
Ma, Lanping
;
Meng, Tao
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
tissue factor
triple negative breast cancer
pancreatic adenocarcinoma
metastasis
antibody-drug conjugate
Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168
作者:
He, Jin-Xue
;
Wang, Meng
;
Huan, Xia-Juan
;
Chen, Chuan-Huizi
;
Song, Shan-Shan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
MPH
PARP inhibitor
homologous recombination
antitumor activity
synthetic lethality
TGF beta 1 Promotes Gemcitabine Resistance through Regulating the LncRNA-LET/NF90/miR-145 Signaling Axis in Bladder Cancer
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 12, 页码: 3053-3067
作者:
Zhuang, Junlong
;
Shen, Lan
;
Yang, Lin
;
Huang, Xiaojing
;
Lu, Qun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
tumor recurrence
cancer stem-like cells
lncRNA-LET
miRNA biogenesis
bladder cancer
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