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科研机构
上海药物研究所 [36]
内容类型
期刊论文 [36]
发表日期
2020 [4]
2019 [2]
2018 [4]
2017 [3]
2016 [3]
2015 [4]
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Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
Folded or Degraded in Endoplasmic Reticulum
期刊论文
REGULATION OF CANCER IMMUNE CHECKPOINTS: MOLECULAR AND CELLULAR MECHANISMS AND THERAPY, 2020, 卷号: 1248, 页码: 265-294
作者:
Li, Chushu
;
Xia, Bingqing
;
Wang, Sheng
;
Xu, Jie
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
Immune checkpoint proteins
Endoplasmic reticulum
Glycosylation
ER chaperones
ER enzymes
Protein folding
COPII
Vesicle trafficking
ER proteostasis
ER quality control
ER stress
UPR
ERAD
ERLAD
Immunotherapy
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer
期刊论文
CANCER LETTERS, 2020, 卷号: 475, 页码: 22-33
作者:
Xiao, Ruoxuan
;
Ding, Chunyong
;
Zhu, Hongwen
;
Liu, Xia
;
Gao, Jing
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Artemisinin
NSCLC
ASNS
ER stress
Cancer Cell Membrane-Camouflaged Nanorods with Endoplasmic Reticulum Targeting for Improved Antitumor Therapy
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 50, 页码: 46614-46625
作者:
Zhang, Wei
;
Yu, Miaorong
;
Xi, Ziyue
;
Nie, Di
;
Dai, Zhuo
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
rod shape
endoplasmic reticulum-tatgeted
cancer cell membrane coating
intracellular trafficking
pancreatic tumor delivery
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 43, 页码: 21732-21738
作者:
Liu, Bin
;
Zhang, Zhijian
;
Hu, Yanyun
;
Lu, Yan
;
Li, Duanzhuo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
type 2 diabetes
gluconeogenesis
hepatic glucose production
ER stress
USP14
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
Cognitive Impairment and Endoplasmic Reticulum Stress Induced by Repeated Short-Term Sevoflurane Exposure in Early Life of Rats
期刊论文
FRONTIERS IN PSYCHIATRY, 2018, 卷号: 9
作者:
Shen, Fu-Yi
;
Song, Ying-Cai
;
Guo, Fei
;
Xu, Zhen-Dong
;
Li, Qian
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
sevoflurane
repeated exposure
cognitive dysfunction
synaptic plasticity
endoplasmic reticulum stress
TSPA as a novel ATF6 alpha translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 948-953
作者:
Zhou, Tingting
;
Cheng, Yanhua
;
Yan, Wenzhong
;
Shi, Xiaofan
;
Xu, Xin
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
ATF6 alpha
ER stress
insulin resistance
TSPA
T2DM
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
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