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Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载:42/0  |  提交时间:2022/01/18
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics 期刊论文
CHEMICAL COMMUNICATIONS, 2021, 卷号: 57, 期号: 91, 页码: 12098-12110
作者:  Tong, Pei-Hong;  Zhu, Ling;  Zang, Yi;  Li, Jia;  He, Xiao-Peng
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/16
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:36/0  |  提交时间:2021/11/04
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载:49/0  |  提交时间:2021/11/04
From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer 期刊论文
ADVANCED MATERIALS, 2021, 页码: 37
作者:  Saeed, Madiha;  Chen, Fangming;  Ye, Jiayi;  Shi, Yang;  Lammers, Twan
收藏  |  浏览/下载:38/0  |  提交时间:2021/08/17
Biomimetic camouflage delivery strategies for cancer therapy 期刊论文
NANOSCALE, 2021, 页码: 14
作者:  Asrorov, Akmal M.;  Gu, Zeyun;  Li, Feng;  Liu, Lingyun;  Huang, Yongzhuo
收藏  |  浏览/下载:23/0  |  提交时间:2021/06/11
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan
收藏  |  浏览/下载:82/0  |  提交时间:2021/06/11
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan
收藏  |  浏览/下载:81/0  |  提交时间:2021/06/11
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhang, Wan-ting;  Liu, Ting-ting;  Wu, Man;  Chen, Xiao-chen;  Han, Li
收藏  |  浏览/下载:53/0  |  提交时间:2021/05/24
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li
收藏  |  浏览/下载:77/0  |  提交时间:2021/06/11


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