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A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS 期刊论文
ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13
作者:  Chang, Lu;  Lin, Feifei;  Cheng, Kai;  Li, Jiaomeng;  Sun, Xiaochu
收藏  |  浏览/下载:59/0  |  提交时间:2022/01/18
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:92/0  |  提交时间:2021/11/04
Fast determination of 16 circulating neurotransmitters and their metabolites in plasma samples of spontaneously hypertensive rats intervened with five different Uncaria 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1179, 页码: 9
作者:  Gao, Lei;  Zhang, Zijia;  Feng, Zijin;  Wei, Wenlong;  Wu, Wenyong
收藏  |  浏览/下载:49/0  |  提交时间:2021/11/04
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:  Qiu, Yanan;  Tang, Chongzhuang;  Li, Ranran;  Cao, Sumin;  Zhang, Yuqiang
收藏  |  浏览/下载:28/0  |  提交时间:2020/12/24
LysargiNase and Chemical Derivatization Based Strategy for Facilitating In-Depth Profiling of C-Terminome 期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 22, 页码: 14522-14529
作者:  Hu, Hao;  Zhao, Wensi;  Zhu, Mengdi;  Zhao, Lei;  Zhai, Linhui
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
pretreatmentwithbroadspectrumantibioticsaltersthepharmacokineticsofmajorconstituentsofshaoyaogancaodecoctioninratsafteroraladministration 期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 002, 页码: 288
作者:  Meng Liu;  Jie Yuan;  Wenjuan Hu;  Changqiang Ke;  Yifan Zhang
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
Development and validation of a highly sensitive LC-MS/MS method for determination of brain active agent dianhydrogalactitol in mouse plasma and tissues: Application to a pharmacokinetic study 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 卷号: 1087, 页码: 90-97
作者:  Sun, Lihan;  Wu, Huajing;  Ren, Lianjie;  Cong, Jiaojiao;  Qin, Xiaohui
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Pretreatment with broad-spectrum antibiotics alters the pharmacokinetics of major constituents of Shaoyao-Gancao decoction in rats after oral administration 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Liu, Meng;  Yuan, Jie;  Hu, Wen-Juan;  Ke, Chang-Qiang;  Zhang, Yi-Fan
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:  Liu, Cai;  Lu, Youming;  Sun, Hongbin;  Yang, Jin;  Liu, Yongqiang
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 24, 页码: 11050-11068
作者:  Liu, Gang;  Xue, Ding;  Yang, Jun;  Wan, Juan;  Liu, Xiaohua
收藏  |  浏览/下载:54/0  |  提交时间:2019/01/08


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