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Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
收藏  |  浏览/下载:32/0  |  提交时间:2021/12/01
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载:47/0  |  提交时间:2021/08/17
Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of alpha,beta-Unsaturated Ketones 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 3, 页码: 908-913
作者:  Liu, Sixiu;  Qi, Jingjing;  Lu, Weiwei;  Wang, Xuan;  Lu, Xiaojie
收藏  |  浏览/下载:12/0  |  提交时间:2021/05/24
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice 期刊论文
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:  Zhao, Jie;  Xie, Cen;  Wang, Kanglong;  Takahashi, Shogo;  Krausz, Kristopher W.
收藏  |  浏览/下载:50/0  |  提交时间:2020/12/21
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
收藏  |  浏览/下载:47/0  |  提交时间:2020/07/01
A Concise and Efficient Approach to 2,6-Disubstituted 4-Fluoropyrimidines from alpha-CF3 Aryl Ketones 期刊论文
SYNTHESIS-STUTTGART, 2020, 卷号: 52, 期号: 2, 页码: 273-280
作者:  Liu, Fangran;  Zhang, Xiaofei;  Qian, Qun;  Yang, Chunhao
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun
收藏  |  浏览/下载:75/0  |  提交时间:2020/07/01
Discovery of pyrrolo[3,2-d]pyrimidine-containing compounds as inhibitors of NIK kinase 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 卷号: 258, 页码: 1
作者:  Zhao, Yu-Jun;  Li, Zhiqiang;  Yan, Ziqing;  Lv, Xilin
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:  Diao, Yanyan;  Fang, Xiaoyu;  Song, Peiran;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:  Xu, Mingming;  Loa-Kum-Cheung, Wendy;  Zhang, Haiyan;  Quinn, Ronald J.;  Mellick, George D.
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01


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