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Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:  Yin, Jianpeng;  Zhan, Desheng;  Ma, Hui;  Liu, Huanan;  Yu, Lifang
收藏  |  浏览/下载:36/0  |  提交时间:2021/12/16
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:93/0  |  提交时间:2021/11/04
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum 期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:  Gao, Yuxiong;  Chen, Zhendong;  Yang, Changyong;  Zhong, Dafang
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/04
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载:22/0  |  提交时间:2021/08/17
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal T-reg cells 期刊论文
NATURE NEUROSCIENCE, 2021, 页码: 33
作者:  Xu, Zhipeng;  Zhang, Xiaoyun;  Chang, Hao;  Kong, Yue;  Ni, Yangyue
收藏  |  浏览/下载:86/0  |  提交时间:2021/05/24
Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus 期刊论文
NEUROSCIENCE LETTERS, 2021, 卷号: 744, 页码: 7
作者:  Abame, Melkamu Alemu;  He, Yang;  Wu, Song;  Xie, Zhifei;  Zhang, Jian
收藏  |  浏览/下载:25/0  |  提交时间:2021/05/24
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li
收藏  |  浏览/下载:77/0  |  提交时间:2021/06/11
Original Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 129, 页码: 10
作者:  Sun, Jingchao;  Xu, Wenjie;  Hua, Huaijie;  Xiao, Ying;  Chen, Xiaoyan
收藏  |  浏览/下载:21/0  |  提交时间:2020/12/24
Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975
作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01
Sub-anesthetic and anesthetic ketamine produce different long-lasting behavioral phenotypes (24 h post-treatment) via inducing different brain derived neurotrophic factor (BDNF) expression level in the hippocampus 期刊论文
NEUROBIOLOGY OF LEARNING AND MEMORY, 2020, 卷号: 167, 页码: 10
作者:  Wu, Chunhui;  Wang, Yu;  He, Yang;  Wu, Song;  Xie, Zhifei
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01


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