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CORC

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PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：130/0  |  提交时间：2021/05/24
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng
收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483
作者:  Zhu, Kongkai;  Jiang, Chengshi;  Tao, Hongrui;  Liu, Jingqiu;  Zhang, Hua
收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08
Detection of PRMT1 inhibitors with stopped flow fluorescence 期刊论文
Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 6
作者:  Qian, Kun;  Hu, Hao;  Xu, Hui;  Zheng, Y George
收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08
Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4579-4594
作者:  Liu, Qing;  Cai, Xiaoqing;  Yang, Dehua;  Chen, Yi;  Wang, Yafang
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 17, 页码: 3648-3661
作者:  Ye, Yan;  Zhang, Bidong;  Mao, Ruifeng;  Zhang, Chenhua;  Wang, Yulan
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 52, 页码: 26722-26738
作者:  Hu, Hao;  Luo, Cheng;  Zheng, Y. George
收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08

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