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科研机构
上海药物研究所 [105]
内容类型
期刊论文 [105]
发表日期
2021 [9]
2020 [15]
2019 [6]
2018 [8]
2017 [9]
2016 [7]
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Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 100, 页码: 12
作者:
Wang, Lan
;
Zhao, Danfeng
;
Wang, Huan
;
Wang, Lele
;
Liu, Xiaohui
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/12/01
Inflammation
Microglia
LPS
RNA-seq
JAK
STAT signaling pathway
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Synthesis of pyranochalcone derivatives and their inhibitory effect on NF-kappa B activation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 5
作者:
Ajiaikebaier, Dilidaer
;
Li, Zuopeng
;
Lin, TzuChun
;
Sun, Xinyu
;
Wang, Bianlin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Pyranochalcone derivatives
NF-kappa B inhibitor
Anti-inflammatory
Inflammatory factor
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway
期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1
作者:
Gao,Xuejie
;
Li,Bo
;
Ye,Anqi
;
Wang,Houcai
;
Xie,Yongsheng
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2021/06/11
Multiple myeloma
Anti-tumor activity
NF-κB
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-kappa B pathway
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:
Gao, Xuejie
;
Li, Bo
;
Ye, Anqi
;
Wang, Houcai
;
Xie, Yongsheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Multiple myeloma
Anti-tumor activity
NF-kappa B
Pharmacological inhibition of NF-kappa B-inducing kinase (NIK) with small molecules for the treatment of human diseases
期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 卷号: 12, 期号: 4, 页码: 552-565
作者:
Cheng, Jing
;
Feng, Xuexin
;
Li, Zhiqiang
;
Zhou, Feilong
;
Yang, Jin-Ming
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/08/17
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:
Chen, Yun
;
Ning, Yi
;
Bai, Gang
;
Tong, Linjiang
;
Zhang, Tao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
IRAK4
PROTAC
protein degrader
scaffolding role
diffuse large B-cell lymphoma
A novel salviadione derivative, compound 15a, attenuates diabetes-induced renal injury by inhibiting NF-kappa B-mediated inflammatory responses
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 409, 页码: 11
作者:
Li, Li
;
Ding, Chunyong
;
Zou, Chunpeng
;
Xiong, Zhi
;
Zhu, Weiwei
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2021/05/24
Salviadione derivative 15a
Diabetic nephropathy
Inflammation
Macrophage infiltration
Fibrosis
Nuclear factor-kappa B
Cytokines
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