CORC

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CORC

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The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 8, 页码: 3898-3923
作者:  Liang, Xuewu;  Zang, Jie;  Li, Xiaoyang;  Tang, Shuai;  Huang, Min
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6018-6035
作者:  Zhu, Wei;  Chen, Hui;  Wang, Yulan;  Wang, Jiang;  Peng, Xia
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776
作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Identification of novel inhibitors of Aurora A with a 3-(pyrrolopyridin-2-yl)indazole scaffold 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 8, 页码: 1858-1868
作者:  Song, Pinrao;  Chen, Ming;  Ma, Xiaodong;  Xu, Lei;  Liu, Tao
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
Design, synthesis, and biological evaluation of novel 2-methylpiperazine derivatives as potent CCR5 antagonists 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 5, 页码: 1157-1168
作者:  Hu, Suwen;  Wang, Zhilong;  Hou, Tingjun;  Ma, Xiaodong;  Li, Jing
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 6, 页码: 673-678
作者:  Zhan, Zhengsheng;  Ai, Jing;  Liu, Qiufeng;  Ji, Yinchun;  Chen, Tiantian
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
Discovery of a New Series of Naphthamides as Potent VEGFR-2 Kinase Inhibitors 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 5, 页码: 592-597
作者:  Lv, Yongcong;  Li, Mengyuan;  Liu, Ting;  Tong, Linjiang;  Peng, Ting
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
The discovery and optimization of novel dual inhibitors of topoisomerase ii and histone deacetylase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 22, 页码: 6981-6995
作者:  Zhang, Xuan;  Bao, Bin;  Yu, Xiuhua;  Tong, Linjiang;  Luo, Yu
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08

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