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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei
收藏  |  浏览/下载:23/0  |  提交时间:2022/01/04
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:  Tian, Junjun;  Lei, Peng;  He, Yifei;  Zhang, Ning;  Ge, Xinyu
收藏  |  浏览/下载:49/0  |  提交时间:2021/11/04
Molecular simulation studies of the interactions between the human/ pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein 期刊论文
BIOCHIMIE, 2021, 卷号: 187, 页码: 1-13
作者:  Ma, Shaojie;  Li, Hui;  Yang, Jun;  Yu, Kunqian
收藏  |  浏览/下载:68/0  |  提交时间:2021/08/17
Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10
作者:  Chen, Meng-Ting;  Huang, Jun-Shang;  Gao, Ding-Ding;  Li, Ying-Xia;  Wang, He-Yao
收藏  |  浏览/下载:41/0  |  提交时间:2021/08/17
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941
作者:  Liu, Yanjun;  Li, Jiacheng;  Liao, Liping;  Huang, Heming;  Fan, Shijie
收藏  |  浏览/下载:21/0  |  提交时间:2021/08/17
Pharmacological inhibition of NF-kappa B-inducing kinase (NIK) with small molecules for the treatment of human diseases 期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 卷号: 12, 期号: 4, 页码: 552-565
作者:  Cheng, Jing;  Feng, Xuexin;  Li, Zhiqiang;  Zhou, Feilong;  Yang, Jin-Ming
收藏  |  浏览/下载:13/0  |  提交时间:2021/08/17
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载:19/0  |  提交时间:2021/05/24
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载:40/0  |  提交时间:2021/06/11
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载:40/0  |  提交时间:2021/05/24
Open Program of the Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences[AMHD-2018-6] 项目
项目编号: AMHD-2018-6, 资助机构: Open Program of the Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载:7/0  |  提交时间:2021/05/24


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