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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
发表日期
2020 [1]
2018 [3]
2016 [1]
2014 [1]
2012 [1]
2011 [1]
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AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Proteomics analysis reveals a potential new target protein for the lipid-lowering effect of Berberine8998
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1473-1482
作者:
Yu, Cheng-yin
;
Liu, Gang-yi
;
Liu, Xiao-hui
;
Gui, Yu-zhou
;
Liu, Hai-ming
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities
期刊论文
FITOTERAPIA, 2018, 卷号: 128, 页码: 102-111
作者:
Li, Jun
;
Li, Hui-hui
;
Wang, Wen-qiong
;
Song, Wei-bin
;
Wang, Yi-ping
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Euphorbia helioscopia
Jatrophanes
Hyperlipidemia
Lipid-lowering
LDL receptor
Optimal extraction of Phaeoporus obliquus saponins and its scavenging effect on fat accumulation in HepG2 cells
期刊论文
Journal of Jilin Univeristy. Medicine edition, 2018, 卷号: 44, 期号: 3, 页码: 526-531
作者:
Zhang Lei
;
Zhang Kun
;
Wang Deli
;
Ren Xiaohong
;
Cui Na
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Phaeoporus obliquus
saponins
HepG2 cells
triglyceride
fat accumulation
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity
期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2014, 卷号: 9, 页码: 4829-4846
作者:
Yuan, Qing
;
Han, Jing
;
Cong, Wenshu
;
Ge, Ying
;
Ma, Dandan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
docetaxel
docetaxel-loaded solid lipid nanoparticles
breast cancer
toxicity
Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice
期刊论文
DIABETOLOGIA, 2012, 卷号: 55, 期号: 5, 页码: 1469-1481
作者:
Huang, S. -L.
;
Yu, R. -T.
;
Gong, J.
;
Feng, Y.
;
Dai, Y. -L.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
Gluconeogenesis
Glucose uptake
Lipid synthesis
Mitochondria
Natural compound
Respiratory complex I
Reduction of Lipid Accumulation in HepG2 Cells by Luteolin is associated with Activation of AMPK and Mitigation of Oxidative Stress
期刊论文
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 4, 页码: 588-596
作者:
Liu, Jin-Feng
;
Ma, Ying
;
Wang, Ying
;
Du, Zhi-Yan
;
Shen, Jing-Kang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
luteolin
AMPK
SREBP-1c
FAS
CPT-1
reactive oxygen species
The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo
期刊论文
PHARMACOLOGICAL RESEARCH, 2007, 卷号: 56, 期号: 4, 页码: 335-343
作者:
Li, Ying-Yin
;
Wu, Hao-Shu
;
Tang, Lei
;
Feng, Chu-Rui
;
Yu, Juan-Hong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
GY3
insulin sensitizing
adipocytokines
antidiabetes
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