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科研机构
上海药物研究所 [81]
内容类型
期刊论文 [76]
会议论文 [5]
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2021 [3]
2020 [6]
2019 [5]
2018 [5]
2017 [6]
2016 [6]
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Pharmacolo... [3]
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Research Progress in Chinese Herbal Medicines for Treatment of Sepsis: Pharmacological Action, Phytochemistry, and Pharmacokinetics
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 20, 页码: 27
作者:
Cheng, Chen
;
Yu, Xuan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/16
antiseptic actions
Chinese herbal medicines
material basis
Qingwen Baidu decoction
Shengfu injection
Shengmai
sepsis
Xuanbai Chengqi decoction
XueBiJing injection
Nyctinastic herbs decoction improves para-chlorophenylalanine-induced insomnia by regulating the expression level of neurotransmitters
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 20, 页码: 16
作者:
Yang, Yiwen
;
Wu, You
;
Xu, Peiqin
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/16
Nyctinastic herbs decoction (NHD)
para-chlorophenylalanine (PCPA)
insomnia
electroencephalograph (EEG)
behavior
neurotransmitters
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Hao-jv
;
An, Yaling
;
Qu, Hua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
Inhibitory effect
Frequently-used traditional Chinese medicines
Isoform-specific probe
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:
Zhao, Shuang
;
Zhu, Yan-Yan
;
Wang, Xiao-Yu
;
Liu, Yong-Sheng
;
Sun, Yun-Xiang
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  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
SIRT6
inhibitor
nature molecule
molecular dynamics simulation
scutellarin
hydrophobic interactions
pi-stacking interactions
binding sites
An integrated strategy for holistic quality identification of Chinese patent medicine:Liuwei Dihuang Pillsas a case study
期刊论文
PHYTOCHEMICAL ANALYSIS, 2020, 页码: 15
作者:
Wang, Xia
;
Wu, Wenyong
;
Zhang, Jianqing
;
Gao, Lei
;
Zhang, Linlin
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  |  
浏览/下载:64/0
  |  
提交时间:2020/12/24
characteristic compound
holistic identification
LC-MS
LWDHP
multivariate statistical analysis
Metabolomics Combined with Multivariate Statistical Analysis for Screening of Chemical Markers between Gentiana scabra and Gentiana rigescens
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 5, 页码: 17
作者:
Zhang, Gaole
;
Li, Yun
;
Wei, Wenlong
;
Li, Jiayuan
;
Li, Haoju
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  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Gentianae Radix et Rhizome
Gentiana scabra
Gentiana rigescens
metabolomics
UPLC
LTQ-Orbitrap-MS
chemical markers
Systematic investigation on the chemical basis of anti-NAFLD Qushi Huayu Fang. Part 1: A study of metabolic profiles in vivo and in vitro by high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 15
作者:
Liu, Huan
;
Sun, Zhaolin
;
Tian, Xiaoting
;
Feng, Qin
;
Guo, Ziqiong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
HPLC-Q-TOF
intestinal bacteria
liver
metabolism
Qushi Huayu Fang
Inhibition of human thrombin by the constituents of licorice: inhibition kinetics and mechanistic insights through in vitro and in silico studies
期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 7, 页码: 3626-3635
作者:
Shi, Cheng-Cheng
;
Chen, Tian-Ran
;
Zhang, Qi-Hua
;
Wei, Ling-Hua
;
Huang, Chao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Current trends in drug metabolism and pharmacokinetics
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
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