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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
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2021 [3]
2020 [4]
2019 [2]
2017 [3]
2016 [1]
2015 [2]
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Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 1, 页码: 283-299
作者:
Li, Jinyang
;
Lu, Jiasheng
;
Guo, Haiyan
;
Zhou, Jianfen
;
Wang, Songli
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Liposome
mn
c(RGDyK)
Immune opsonization
Immunogenicity
Anti-glioma efficacy
UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 6, 页码: 491-499
作者:
Chen, Wei-Ying
;
Liang, Guang-Yan
;
Zheng, Zuo-Liang
;
Wu, Yun-Shan
;
Xu, Fang-Fang
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
Protosappanin B
Metabolic pathways
UPLC-TOF-MS
MS
Plasma
Bile
Feces
Urine
Intestinal bacteria sample
Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6
作者:
Hu, Wen-juan
;
Chang, Lu
;
Yang, Ying
;
Wang, Xin
;
Xie, Yuan-chao
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/21
remdesivir
pharmacokinetics
tissue distribution
nucleotide monophosphate
nucleotide triphosphate
nucleoside
An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition
期刊论文
BIOMATERIALS, 2020, 卷号: 257, 页码: 13
作者:
Wang, Kaiyuan
;
Ye, Hao
;
Zhang, Xuanbo
;
Wang, Xia
;
Yang, Bin
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/24
Exosome membrane
Cucurbitacin B
Paclitaxel
Breast cancer metastasis
Programmable bioactivation
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
;
Wang, Yun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2019, 卷号: 84, 期号: 2, 页码: 373-382
作者:
Petain, Aurelie
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Vinorelbine
Non-small-cell lung cancer
Breast cancer
China
Pharmacokinetics
Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 4, 页码: 364-376
作者:
Wang, Fengling
;
Wu, Yifan
;
Zhang, Jiwen
;
Wang, Huihui
;
Xie, Xiaoting
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
Amyloid beta: structure, biology and structure-based therapeutic development
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235
作者:
Chen, Guo-fang
;
Xu, Ting-hai
;
Yan, Yan
;
Zhou, Yu-ren
;
Jiang, Yi
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
amyloid beta peptide
amyloid precursor protein
Alzheimer's disease
neurodegenerative diseases
drug discovery
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