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科研机构
上海药物研究所 [15]
内容类型
期刊论文 [15]
发表日期
2021 [2]
2020 [1]
2019 [2]
2018 [4]
2017 [2]
2016 [1]
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Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 18
作者:
Lin, Zemin
;
Liu, Yuting
;
Chen, Li
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
artemisinin analog
antiphospholipid syndrome
antiphospholipid syndrome nephropathy associated lupus nephritis
oxidative stress
inflammation
Nrf2
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice
期刊论文
LIFE SCIENCES, 2019, 卷号: 232, 页码: 9
作者:
Dong, Yunxia
;
Lu, Henglei
;
Li, Qiang
;
Qi, Xinming
;
Li, Yuanchao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
(5R)-5-hydroxytriptolide
NAFLD
Lipid synthesis
Fatty acids oxidation
Fat deposition
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Diao, Xingxing
;
Huestis, Marilyn A.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
novel psychoactive substances
NPS
synthetic cannabinoid
SC
metabolism
urinary metabolites
hepatocyte incubation
Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 2, 页码: 823-834
作者:
Xie, Yongsheng
;
Li, Bo
;
Bu, Wenxuan
;
Gao, Lu
;
Zhang, Yong
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
mantle cell lymphoma
dihydrocelastrol
apoptosis
cell cycle
mTORC1
mTORC2
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fc gamma receptor signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 1, 页码: 107-116
作者:
Qi, Qing
;
Li, Heng
;
Lin, Ze-min
;
Yang, Xiao-qian
;
Zhu, Feng-hua
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fc gamma receptor signaling
5r5hydroxytriptolideamelioratesantiglomerularbasementmembraneglomerulonephritisinnzwmicebyregulatingfcyreceptorsignaling
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcy receptor signaling
期刊论文
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/12/24
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling
Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:
Chen, Wen-hua
;
Song, Shan-shan
;
Qi, Ming-hui
;
Huan, Xia-juan
;
Wang, Ying-qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
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