CORC

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CORC

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Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong
收藏  |  浏览/下载：73/0  |  提交时间：2022/01/04
Increasing the Sampling Efficiency of Protein Conformational Change by Combining a Modified Replica Exchange Molecular Dynamics and Normal Mode Analysis 期刊论文
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2021, 卷号: 17, 期号: 1, 页码: 13-28
作者:  Peng, Cheng;  Wang, Jinan;  Shi, Yulong;  Xu, Zhijian;  Zhu, Weiliang
收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24
A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma 期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 12, 页码: 3256-3267
作者:  Sun, Jingya;  Wang, Xin;  Tang, Boyun;  Liu, Hongchun;  Zhang, Minmin
收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08
Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 122-132
作者:  Liu, Yang;  Peng, Xia;  Guan, Xiaocong;  Lu, Dong;  Xi, Yong
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08
Energetics and structural characterization of the "DFG-flip'' conformational transition of B-RAF kinase: a SITS molecular dynamics study 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 2, 页码: 1257-1267
作者:  Shao, Qiang;  Xu, Zhijian;  Wang, Jinan;  Shi, Jiye;  Zhu, Weiliang
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 43, 页码: 69945-69960
作者:  Zhang, Xin;  Jia, Deyong;  Ao, Junping;  Liu, Huijuan;  Zang, Yi
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells 期刊论文
CLINICAL CANCER RESEARCH, 2015, 卷号: 21, 期号: 4, 页码: 833-843
作者:  Wu, Lixian;  Yu, Jing;  Chen, Ruijia;  Liu, Yang;  Lou, Liguang
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
Curcumin derivative C817 inhibits proliferation of imatinib-resistant chronic myeloid leukemia cells with wild-type or mutant Bcr-Abl in vitro 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 3, 页码: 401-409
作者:  Wu, Li-xian;  Wu, Ying;  Chen, Rui-jia;  Liu, Yang;  Huang, Li-sen
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants 期刊论文
CANCER SCIENCE, 2014, 卷号: 105, 期号: 1, 页码: 117-125
作者:  Zhao, Jie;  Quan, Haitian;  Xu, Yongping;  Kong, Xiangqian;  Jin, Lu
收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting Epidermal Growth Factor Receptor Threonine(790) -> Methionine(790) Mutant 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 6, 页码: 2711-2723
作者:  Chang, Shaohua;  Zhang, Lianwen;  Xu, Shilin;  Luo, Jinfeng;  Lu, Xiaoyun
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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