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Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载:41/0  |  提交时间:2021/08/17
Structural basis for activation of the growth hormone-releasing hormone receptor 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:  Zhou, Fulai;  Zhang, Huibing;  Cong, Zhaotong;  Zhao, Li-Hua;  Zhou, Qingtong
收藏  |  浏览/下载:24/0  |  提交时间:2020/12/21
Assessing AMBER force fields for protein folding in an implicit solvent 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2018, 卷号: 20, 期号: 10, 页码: 7206-7216
作者:  Shao, Oiang;  Zhu, Weiliang
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes 期刊论文
PHARMACOLOGICAL REVIEWS, 2016, 卷号: 68, 期号: 4, 页码: 954-1013
作者:  de Graaf, Chris;  Donnelly, Dan;  Wootten, Denise;  Lau, Jesper;  Sexton, Patrick M.
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R) 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 25, 页码: 12991-13004
作者:  Yang, Dehua;  de Graaf, Chris;  Yang, Linlin;  Song, Gaojie;  Dai, Antao
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Proteoglycans and Glycosaminoglycans in Misfolded Proteins Formation in Alzheimer's Disease 期刊论文
PROTEIN AND PEPTIDE LETTERS, 2014, 卷号: 21, 期号: 10, 页码: 1048-1056
作者:  Wang, Peipei;  Ding, Kan
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Microsecond molecular dynamics simulation of A beta(42) and identification of a novel dual inhibitor of A beta(42) aggregation and BACE1 activity 期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9, 页码: 1243-1250
作者:  Wang, Yuan-yuan;  Li, Li;  Chen, Tian-tian;  Chen, Wu-yan;  Xu, Ye-chun
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Structure of the human glucagon class B G-protein-coupled receptor 期刊论文
NATURE, 2013, 卷号: 499, 期号: 7459, 页码: 444-+
作者:  Siu, Fai Yiu;  He, Min;  de Graaf, Chris;  Han, Gye Won;  Yang, Dehua
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Design of Cell-Permeable Stapled Peptides as HIV-1 Integrase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 13, 页码: 5601-5612
作者:  Long, Ya-Qiu;  Huang, Shao-Xu;  Zawahir, Zahrah;  Xu, Zhong-Liang;  Li, Huiyuan
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
microsecondmoleculardynamicssimulationofa42andidentificationofanoveldualinhibitorofa42aggregationandbace1activity 期刊论文
actapharmacologicasinica, 2013, 卷号: 34, 期号: 9, 页码: 1243
作者:  Wang Yuanyuan;  Li Li;  Chen Tiantian;  Chen Wuyan;  Xu Yechun
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01


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