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上海药物研究所 [8]
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期刊论文 [36]
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Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing
期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:
Mao, Rui
;
Zhang, Xiaoyun
;
Kong, Youyong
;
Wu, Shanshan
;
Huo, Hai-qin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
anaplastic lymphoma kinase
cerebral organoid
neurodevelopment
neural progenitor cell
single-cell RNA sequencing
Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Li, Yan-Fen
;
Zheng, Yue-Ming
;
Yu, Yong
;
Gan, Yong
;
Gao, Zhao-Bing
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Functional inactivation of dorsal medial striatum afters behavioral flexibility and recognition process in mice
期刊论文
PHYSIOLOGY & BEHAVIOR, 2017, 卷号: 179, 期号: 0, 页码: 467-477
作者:
Qiao, Yanhua
;
Wang, Xingyue
;
Ma, Lian
;
Li, Shengguang
;
Liang, Jing
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2017/11/22
Dorsomedial striatum
Neuronal inactivation
Recognition process
Reversal learning
Tetanus toxin light chain
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease
期刊论文
PROTEIN & CELL, 2016, 卷号: 7, 期号: 2, 页码: 114-129
作者:
Song, Pingping
;
Li, Shanshan
;
Wu, Hao
;
Gao, Ruize
;
Rao, Guanhua
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2016/05/09
parkin
sequestosome1/p62
ubiquitin
substantia nigra
Serotonin type-1D receptor stimulation of A-type K+ channel decreases membrane excitability through the protein kinase A- and B-Raf-dependent p38 MAPK pathways in mouse trigeminal ganglion neurons
期刊论文
CELLULAR SIGNALLING, 2016, 卷号: 28, 期号: 8, 页码: 979-988
作者:
Zhao, XY
;
Zhang, Y
;
Qin, WJ
;
Cao, JP
;
Zhang, Y
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/09/14
DORSAL-ROOT GANGLION
KV4.2 POTASSIUM CHANNEL
BETA-GAMMA-SUBUNITS
NEUROPATHIC PAIN
SENSORY NEURONS
ENHANCED EXCITABILITY
INFLAMMATORY PAIN
MELANOMA-CELLS
ACTIVATION
MODULATION
Prefrontal cortex gates acute morphine action on dopamine neurons in the ventral tegmental area
期刊论文
NEUROPHARMACOLOGY, 2015, 卷号: 95, 页码: 299-308
作者:
Liu, Changliang
;
Fang, Xing
;
Wu, Qianqian
;
Jin, Guozhang
;
Zhen, Xuechu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Morphine
Dopamine
Single-unit recording
Ventral tegmental area
Prefrontal cortex
Effects of SKF83959 on the excitability of hippocampal CA1 pyramidal neurons: a modeling study
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 6, 页码: 738-751
作者:
Zhou, Shang-lin
;
Chu, Hong-yuan
;
Jin, Guo-zhang
;
Cui, Jian-min
;
Zhen, Xue-chu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
SKF83959
hippocampus
pyramidal neuron
neuronal modeling
excitability
Na+ channel
EPSP
temporal summation
The Tetramerization Domain Potentiates Kv4 Channel Function by Suppressing Closed-State Inactivation
期刊论文
biophysical journal, 2014
Tang, Yi-Quan
;
Zhou, Jing-Heng
;
Yang, Fan
;
Zheng, Jie
;
Wang, Kewei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
U-TYPE INACTIVATION
INTRACELLULAR T1-T1 INTERFACE
LONG-TERM POTENTIATION
GATED K+ CHANNELS
POTASSIUM CHANNELS
3-DIMENSIONAL STRUCTURE
PYRAMIDAL NEURONS
CALCIUM-CHANNELS
LIVING CELLS
T1 DOMAIN
Conopeptide Vt3.1 Preferentially Inhibits BK Potassium Channels Containing beta 4 Subunits via Electrostatic Interactions*
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 卷号: 289, 期号: 8, 页码: 4735-4742
作者:
Li, M
;
Chang, S
;
Yang, LJ
;
Shi, JY
;
McFarland, K
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2015/07/22
Electrophysiology
Molecular Modeling
Peptide Interactions
Potassium Channels
Toxins
4 Subunit
BK Channel
Activation
Conopeptide
Electrostatic Interaction
Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 6, 页码: 728-736
作者:
Li, Ping
;
Sun, Hai-feng
;
Zhou, Ping-zheng
;
Ma, Chao-ying
;
Hu, Guo-yuan
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
dofetilide
DC031050
class III antiarrhythmic agent
hERG
KCNQ
Kv1.2
delayed rectifier potassium current
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