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昆明动物研究所 [4]
上海药物研究所 [3]
昆明医科大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [9]
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2019 [1]
2014 [4]
2012 [2]
2008 [2]
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Polymorphism rs2395655 affects LEDGF/p75 binding activity and p21WAF1/CIP1 gene expression in esophageal squamous cell carcinoma
期刊论文
2019, 卷号: 8, 期号: 5, 页码: 2313-2324
作者:
Guo, Rong
;
Ma, Yunan
;
Zhao, Min
;
Zhang, Wenlong
;
An, Guo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
esophageal squamous cell carcinoma
lens epithelium-derived growth factor
p21WAF1/CIP1
prognostic factor
single-nucleotide polymorphism
Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2014, 卷号: 12, 期号: 3
作者:
Zheng Yong-Tang
;
Zhang Xuan
;
Huang Sheng-Zhuo
;
Gu Wan-Gang
;
Yang Liu-Meng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/04
Wikstroelide M
Daphnane diterpene
Daphne acutiloba Rehder
HIV
Reverse trascriptase
integrase
Nuclear translocation
Lens epithelium-derived growth factor (LEDGF/p75)
Molecular docking
Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation
期刊论文
Chinese Journal of Natural Medicines, 2014, 卷号: 12, 期号: 3, 页码: 186-193
作者:
Zhang X
;
Huang SZ
;
Gu WG
;
Yang LM
;
Chen H
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2014/06/03
Wikstroelide M
Daphnane diterpene
Daphne acutiloba Rehder
HIV
Reverse trascriptase
integrase
Nuclear translocation
Lens epithelium-derived growth factor (LEDGF/p75)
Molecular docking
Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging
期刊论文
FEBS LETTERS, 2014, 卷号: 588, 期号: 18, 页码: 3461-3468
作者:
Gu WG
;
Zhang X
;
Ip DTM
;
Yang LM
;
Zheng YT
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2014/10/10
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/P75)
Virtual screening
1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 213, 期号: X, 页码: 21-27
作者:
Gu WG
;
Ip DTM
;
Liu SJ
;
Chan JH
;
Wang Y
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2014/10/15
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/P75
Molecular docking
Inhibitors of HIV-1 Integrase-Human LEDGF/p75 Interaction Identified from Natural Products via Virtual Screening
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 12, 页码: 2752-2758
作者:
Hu Guoping
;
Li Xi
;
Li Yaozong
;
Sun Xianqiang
;
Liu Guixia
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
natural products
virtual screening
protein-protein interaction
HIV-1 integrase
human LEDGF
p75 protein
Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking
期刊论文
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 12, 页码: 4995-5003
作者:
Hu, Guoping
;
Li, Xi
;
Sun, Xianqiang
;
Lu, Weiqiang
;
Liu, Guixia
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Drug repositioning
HIV-1 Integrase
Human LEDGF/p75 protein
Molecular docking
Protein-protein interaction
D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 卷号: 375, 期号: 1, 页码: 139-144
作者:
Du, Li
;
Chen, Jing
;
Yang, Liumeng
;
Zheng, Yongtang
;
Tang, Yun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/p75)
yeast two-hybrid assay
surface plasmon resonance (SPR)
molecular docking
site-directed mutagenesis
D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 卷号: 375, 期号: 1, 页码: 139-144
作者:
Du L
;
Chen JX
;
Chen J
;
Yang LM
;
Zheng YT
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2010/08/24
HIV-1 integrase
Lens epithelium-derived growth factor (LEDGF/p75)
yeast two-hybrid assay
surface plasmon resonance (SPR)
molecular docking
site-directed mutagenesis
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