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Crystalline form of 3-(3-{ 2-[(e)-3, 5-diamino-6-chloro-pyrazine-2-carbonylimino]-1, 3, 8-triaza-spiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester succinate 专利
作者:  TUFILLI NICOLA;  HOWSHAM CATHERINE;  LINDENBERG CHRISTIAN;  PERLBERG ANETT
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Compounds acid derivatives 3- [...] -propionic acid substituted; protease cathepsin inhibitor to; process of preparation; pharmaceutical composition; and their use for treating heart failure, myocardial infarction, hypertension, rheumatoid arthritis, renal failure asthma, cystic [...] , chronic bronchitis, thrombosis, pain. 专利
作者:  RUF SVEN;  PERNERSTORFER JOSEF;  SADOWSKI THORSTEN;  SCHREUDER HERMAN;  BUNING CHRISTRIAN
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/05
Crystalline form c succinate ester [...] of 3-(3-{ 2-[ (e)-3.5-diamino-6-chloro-pyrazine-2- [...] ]-1.3, 8-triaza-spiro [4.5] decane-8-carbonyl}-benzenesulfonylamino)-propionic acid; pharmaceutical composition and inhalation device comprising; and their use for the treatment of respiratory diseases such as asthma and [...]. 专利
作者:  NICOLA TUFILLI;  CATHERINE HOWSHAM;  CHRISTIAN LINDERBERG;  ANETT PERLBERG
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Compounds derived from 3- [...] -propionic acid substituted, as inhibitors of the protease cathepsin to; procedure of preparation; pharmaceutical composition comprising the same; and its use for the treatment of heart failure, immunological diseases, asthma, pain, among others. 专利
作者:  RUF SVEN;  SADOWSKI THORSTEN;  WIRTH KLAUS;  SCHREUDER HERMAN;  BUNING CHRISTIAN
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3-AMINO-2-(4-AMINOCARBONYLOXY)PHENYL-PROPIONIC ACID DERIVATIVES AS ALPHA-4- INTEGRIN INHIBITORS 专利
作者:  KONRADI, ANDREI W.;  PLEISS, MICHAEL A.;  THORSETT, EUGENE D.;  ASHWELL, SUSAN;  WELMAKER, GREGORY S.
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INDOLE-3-PROPIONIC ACIDS, SALTS AND ESTERS THEREOF USED AS MEDICAMENTS 专利
作者:  PAPPOLLA MIGUEL A;  FRANGIONE BRAS;  GHISO JORGE;  POEGGELER BURKHARD
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