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上海药物研究所 [12]
心理研究所 [4]
计算技术研究所 [3]
合肥物质科学研究院 [3]
西北高原生物研究所 [2]
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期刊论文 [29]
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2021 [29]
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An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments
期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:
Pang, Keliang
;
Jiang, Richeng
;
Zhang, Wei
;
Yang, Zhengyi
;
Li, Lin-Lin
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2021/12/27
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments
期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:
Pang, Keliang
;
Jiang, Richeng
;
Zhang, Wei
;
Yang, Zhengyi
;
Li, Lin-Lin
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/28
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
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  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Mechanism of Fuzheng Kang'ai Formula Regulating Tumor Microenvironment in Non-Small Cell Lung Cancer
期刊论文
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2021, 页码: 9
作者:
Tian Yun-ling
;
Fu Song-bo
;
Li Bo
;
Yuan Ling-yan
;
Bing Zhi-tong
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  |  
浏览/下载:18/0
  |  
提交时间:2021/12/08
network pharmacology
prognosis
tumor microenvironment
Fuzheng Kang'ai Formula
Chinese medicine
lung adenocarcinoma
FALCON2: a web server for high-quality prediction of protein tertiary structures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 14
作者:
Kong, Lupeng
;
Ju, Fusong
;
Zhang, Haicang
;
Sun, Shiwei
;
Bu, Dongbo
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  |  
浏览/下载:39/0
  |  
提交时间:2021/12/01
Protein structure prediction
Template-based modeling
Ab initio prediction
Protein structure prediction web service
Preservation Analysis on Spatiotemporal Specific Co-expression Networks Suggests the Immunopathogenesis of Alzheimer's Disease
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2021, 卷号: 13, 页码: 12
作者:
Guo, Liyuan
;
Liu, Yushan
;
Wang, Jing
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  |  
浏览/下载:30/0
  |  
提交时间:2021/12/27
Alzheimer's disease
spatiotemporal specific coexpression networks
network preservation analysis
immune response-related pathways
non-neuron cells
key genes
Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction
期刊论文
PHYTOMEDICINE, 2021, 卷号: 90, 页码: 12
作者:
Zhi, Haijuan
;
Zhang, Zijia
;
Deng, Yanping
;
Yan, Bingpeng
;
Li, Zhenwei
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  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
Acute myocardial infarction
Danqi Tongmai tablet
In vivo metabolite
Oxylipin
Arachidonic acid metabolome
Homeostasis
Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5, 页码: 23
作者:
Rahman, Md Habibur
;
Rana, Humayan Kabir
;
Peng, Silong
;
Hu, Xiyuan
;
Chen, Chen
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/12/28
bioinformatics
machine learning
central nervous system disorders
glioblastoma
comorbidity
pathway
ontology
proteins
survival analysis
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:
Lu, Tian
;
Lu, Haibo
;
Duan, Zhe
;
Wang, Jun
;
Han, Jie
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
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