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科研机构
上海药物研究所 [11]
金属研究所 [3]
过程工程研究所 [1]
自动化研究所 [1]
内容类型
期刊论文 [16]
发表日期
2021 [16]
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Cyclic response of additive manufactured 316L stainless steel: The role of cell structures
期刊论文
SCRIPTA MATERIALIA, 2021, 卷号: 205, 页码: 6
作者:
Cui, Luqing
;
Jiang, Fuqing
;
Deng, Dunyong
;
Xin, Tongzheng
;
Sun, Xiaoyu
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  |  
浏览/下载:62/0
  |  
提交时间:2021/11/22
Additive manufacturing
316L stainless steel
Cellular structure
Cyclic response behavior
Deformation mechanism
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 11
作者:
Ma, Shanshan
;
Chen, Yan
;
Dai, Antao
;
Yin, Wanchao
;
Guo, Jia
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  |  
浏览/下载:24/0
  |  
提交时间:2021/11/04
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:
Zhang, Huibing
;
Chen, Li-Nan
;
Yang, Dehua
;
Mao, Chunyou
;
Shen, Qingya
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  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8
作者:
Wang, Xi
;
Cheng, Xi
;
Zhao, Lihua
;
Wang, Yuzhe
;
Ye, Chenyu
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  |  
浏览/下载:25/0
  |  
提交时间:2021/11/04
parathyroid hormone receptor 2
cryo-electron microscopy
G protein-coupled receptor
ligand recognition
syndromic short stature
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 20
作者:
Zhao, Fenghui
;
Zhang, Chao
;
Zhou, Qingtong
;
Hang, Kaini
;
Zou, Xinyu
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  |  
浏览/下载:36/0
  |  
提交时间:2021/08/17
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening
期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:
Zhou, Qingtong
;
Guo, Wanjing
;
Dai, Antao
;
Cai, Xiaoqing
;
Vass, Marton
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
GLP-1R
virtual screening
allosteric modulator
drug discovery
molecular docking
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Cong, Zhaotong
;
Chen, Li-Nan
;
Ma, Honglei
;
Zhou, Qingtong
;
Zou, Xinyu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
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