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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17 作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui 收藏  |  浏览/下载：69/0  |  提交时间：2021/11/04 Tetrahydrobenzo[b]thiophen-2-yl)urea  alpha-Glucosidase inhibitors  Non-competitive inhibitor  Molecular docking  Anti-hyperglycaemic activity  Type 2 diabetes   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor   Neo-clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L. 期刊论文 CHEMISTRY & BIODIVERSITY, 2021, 页码: 6 作者:  Fan, Min;  Wang, Ting;  Peng, Li-Yan;  Huang, Jun-Shang;  Wu, Xing-De 收藏  |  浏览/下载：21/0  |  提交时间：2021/11/04 Salvia hispanica  neo-clerodane diterpenoid  salvihispin H  type 2 diabetes mellitus   A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文 LIFE SCIENCES, 2021, 卷号: 269, 页码: 8 作者:  Yang, Liu;  Lei, Xian-Tao;  Huang, Qi;  Wang, Ting;  Sun, Hong-Bin 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 GPR120 agonist  Insulin secretion  Anti-inflammation  Insulin resistance  Type 2 diabetes mellitus   Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409 作者:  Zhang, Yi-fan;  Liu, Yan-mei;  Yu, Chen;  Wang, Ya-ting;  Zhan, Yan 收藏  |  浏览/下载：68/0  |  提交时间：2021/05/24 diabetes  henagliflozin  pharmacodynamics  pharmacokinetics  SGLT-2 inhibitors   Characterization and quantitative determination of henagliflozin metabolites in humans 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8 作者:  Chen, Zhendong;  Li, Liang;  Zhan, Yan;  Zhang, Yifan;  Liu, Haiyan 收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Henagliflozin  Metabolism  LC-MS/MS