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上海药物研究所 [27]
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期刊论文 [83]
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2020 [85]
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3681-3688
作者:
Yang, Yue
;
Gong, Qi
;
Wang, Wei
;
Mao, Ying-Le
;
Wang, Xiao-Rong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/05/24
Proteoglycan from Bacillus sp. BS11 Inhibits the Inflammatory Response by Suppressing the MAPK and NF-kappa B Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages
期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 12, 页码: 16
作者:
Wang, Qingchi
;
Liu, Weixiang
;
Yue, Yang
;
Sun, Chaomin
;
Zhang, Quanbin
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/04/12
Bacillus sp
proteoglycan
anti-inflammation
macrophages
Sesquiterpene lactone dimers from Artemisia lavandulifolia inhibit interleukin-1 beta production in macrophages through activating autophagy
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 105, 页码: 12
作者:
Wang, Qiaoqiao
;
Zhang, Tian
;
Ke, Chang-Qiang
;
Tang, Chunping
;
Yao, Sheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/05/24
Artemisia lavandulifolia
Sesquiterpene lactone dimers
IL-1 beta
NLRP3
Autophagy
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56
作者:
Xu, Xiaoju
;
Xu, Xu
;
Hao, Yanping
;
Zhu, Xialin
;
Lu, Jian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013
作者:
Chai, Xianzhi
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Li, Na
;
Zang, Yi
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  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 161, 页码: 35-43
作者:
Zeng, Hui
;
Li, Piaopiao
;
Zhou, Lishuang
;
Ding, Kan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/21
Polygala tenuifolia
Pectin
Polysaccharide
A beta(42) Alzheimer's disease
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:
Darbalaei, Sanaz
;
Yuliantie, Elita
;
Dai, Antao
;
Chang, Rulue
;
Zhao, Peishen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
G protein-coupled receptor
Glucagon-like peptide-1 receptor
Glucagon receptor
Biased agonism
Unimolecular dual agonist
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