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科研机构
上海药物研究所 [6]
兰州理工大学 [1]
过程工程研究所 [1]
海洋研究所 [1]
内容类型
期刊论文 [9]
发表日期
2020 [9]
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Cinnamtannin D1 Protects Pancreatic beta-Cells from Glucolipotoxicity-Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 45, 页码: 12617-12630
作者:
Wang, Xin-Yi
;
Zhu, Bo-Rong
;
Jia, Qi
;
Li, Yi-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
cinnamtannin D1
pancreatic beta-cells
autophagy
apoptosis
type 2 diabetes
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115
作者:
Bian, Youcheng
;
Zeng, Hui
;
Tao, Hong
;
Huang, Lulin
;
Du, Zhenyun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Polygala tenuifolia
Pectin
Pancreatic cancer
Apoptosis
Autophagy
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
Drug Delivery System in the Treatment of Diabetes Mellitus
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 页码: 16
作者:
Zhao, Ruichen
;
Lu, Zhiguo
;
Yang, Jun
;
Zhang, Liqun
;
Li, Yan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/10/30
diabetes mellitus
drug delivery
insulin
gene therapy
nanoparticle
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Wei, Yan
;
Song, Sha
;
Duan, Nianxiu
;
Wang, Feng
;
Wang, Yuxi
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/12/24
membrane type 1-matrix metalloproteinase-activated cilengitide
pancreatic cancer
smart liposomes
vascular promotion
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes
期刊论文
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:
Dou, Hui-Xia
;
Wang, Ting
;
Su, Hai-Xia
;
Gao, Ding-Ding
;
Xu, Ye-Chun
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
eFABP4
Adipocyte
Differentiation
Lipolysis
Inflammation
Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic beta-cells protective agents for the treatment of type 2 diabetes mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188, 页码: 17
作者:
Wang, Junwei
;
Lv, Xue
;
Xu, Jiawen
;
Liu, Xinpeng
;
Du, Te
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Type 2 diabetes mellitus
Pancreatic beta-cells protective agents
Vincamine derivatives
Structural modifications
Structure-activity relationships
Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis
期刊论文
Chinese Medicine, 2020, 卷号: 15, 期号: 1, 页码: 1-12.
作者:
Xi Liu
;
Qiong Li
;
Xiaolei Cheng
;
Zhichun Liu
;
Xiaoliang Zhao
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/03/10
Oligomannuronate
Type 2 diabetes
Islet amyloid polypeptide
JNK activation
Mitochondrial dysfunction
RINm5F cells
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