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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Synthesis and biological activity of C-7, C-9 and C-10 modified taxane analogues from 1-deoxybaccatin VI 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 21, 页码: 8 作者:  Xie, Chenghu;  Cui, Yongmei;  Li, Lanlan;  Zhang, Minmin;  Liu, Hongchun 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/21 Paclitaxel  Taxane analogues  1-Deoxybaccatin VI  Synthesis  In vitro anticancer activity   Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352 作者:  Jin, Rui;  Liu, Liang;  Xing, Yun;  Meng, Tao;  Ma, Lanping 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24 An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy 期刊论文 NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 16 作者:  Wang, Cong;  Sun, Wanbing;  Zhang, Jun;  Zhang, Jianping 收藏  |  浏览/下载：27/0  |  提交时间：2020/12/21 SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei 收藏  |  浏览/下载：75/0  |  提交时间：2020/12/21 ROS1 kinase  ROS1 inhibitor  SAF-189s  lorlatinib  crizotinib resistance  G2032R mutant  NSCLC   Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway 期刊论文 FOOD & FUNCTION, 2020, 卷号: 11, 期号: 8, 页码: 6961-6970 作者:  Tao, Hong;  Chen, Xia;  Du, Zhenyun;  Ding, Kan 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 Capsaicin derivatives with nitrothiophene substituents: Design, synthesis and antibacterial activity against multidrug-resistant S. aureus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 198, 页码: 11 作者:  Wang, Zhi-Cheng;  Wei, Bingyan;  Pei, Fang-Ning;  Yang, Teng;  Tang, Jie 收藏  |  浏览/下载：12/0  |  提交时间：2020/12/24 Capsaicin  Nitrothiophene  Multidrug-resistant S. aureus  Antibacterial agent   YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer 期刊论文 BRITISH JOURNAL OF CANCER, 2020, 页码: 12 作者:   收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24 A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe 期刊论文 Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1 作者:   收藏  |  浏览/下载：93/0  |  提交时间：2020/07/01 Multiple myeloma  Drug-resistance  DNA damage response  Cell cycle   Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation 期刊论文 JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026 作者:   收藏  |  浏览/下载：38/0  |  提交时间：2020/12/24 Alflutinib  NSCLC  EGFR T790M mutation  Efficacy  Safety   Accurate prediction of relative binding affinities of a series of HIV-1 protease inhibitors using semi-empirical quantum mechanical charge 期刊论文 JOURNAL OF COMPUTATIONAL CHEMISTRY, 2020, 页码: 8 作者:   收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 adaptive steered molecular dynamics (ASMD)  binding affinity  HIV-1 protease  semi-empirical quantum mechanics