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科研机构
上海药物研究所 [38]
内容类型
期刊论文 [38]
发表日期
2020 [38]
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发表日期:2020
专题:上海药物研究所
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Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
期刊论文
BIOMATERIALS SCIENCE, 2020, 卷号: 8, 期号: 24, 页码: 7166-7176
作者:
Tu, Bin
;
He, Yang
;
Chen, Binfan
;
Wang, Yonghui
;
Gao, Yanrong
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Nostoc sphaeroids Kutz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 1734-1742
作者:
Li, Meixia
;
Guo, Ciliang
;
Wang, Yeqing
;
Du, Zhenyun
;
Chen, Sheng
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
Nostoc sphaeroids Kutz polysaccharide
Nostoc sphaeroids Kutz powder
16S ribosomal RNA gene sequencing
Core bacterial community
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Structural basis for activation of the growth hormone-releasing hormone receptor
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:
Zhou, Fulai
;
Zhang, Huibing
;
Cong, Zhaotong
;
Zhao, Li-Hua
;
Zhou, Qingtong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Cao, Hua
;
Ye, Yangliang
;
Feng, Ying
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/21
Soft drug
TGR5
GLP-1
Gallbladder-filling effects
Rapid metabolism
Carboxylic ester
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