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科研机构
昆明植物研究所 [5]
成都生物研究所 [1]
内容类型
期刊论文 [6]
发表日期
2019 [6]
学科主题
Chemistry ... [1]
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Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:
Chen, Si-Yue
;
Geng, Chang-An
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Yang, Xiao-Tong
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  |  
浏览/下载:139/0
  |  
提交时间:2019/09/10
Gastrodia elata
Polybenzyls
Melatonin receptors
Structure-activity relationships
Docking study
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:
Deng, Guogang
;
Zhou, Bei
;
Wang, Jing
;
Chen, Zhuo
;
Gong, Liang
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  |  
浏览/下载:94/0
  |  
提交时间:2019/07/29
Diosgenin
Cholesterol
Dehydroepiandrosterone
Imidazolium salt
Antitumor activities
Structure-activity relationships
An overview of grayanane diterpenoids and their biological activities from the Ericaceae family in the last seven years
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 400-416
作者:
Li, Chun-Huan
;
Zhang, Jia-Yao
;
Zhang, Xiu-Yun
;
Li, Sheng-Hong
;
Gao, Jin-Ming
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  |  
浏览/下载:96/0
  |  
提交时间:2019/04/15
Grayanane diterpenoids
Ericaceae
Bioactivities
Analgesic activity
Anti-inflammatory activity
PTP1B inhibitory activity
Structure-activity relationship
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:
Chen, Duo-zhi
;
Yang, Bi-juan
;
He, Xiao-li
;
Fan, Shi-rui
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  |  
浏览/下载:114/0
  |  
提交时间:2019/03/18
Wnt/beta-catenin signalling pathway agonist
Phenanthridine derivatives
Structural optimization
Structure-activity relationships (SARs)
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:
Zi, Cheng-Ting
;
Yang, Liu
;
Xu, Feng-Qing
;
Dong, Fa-Wu
;
Ma, Rui-Jing
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  |  
浏览/下载:103/0
  |  
提交时间:2019/03/18
Biodnylated Camptothecin Derivatives
Anticancer Activity
Synthesis
Click Chemistry
Structure-activity Relationships (Sars)
4,6-Substituted-1 H-Indazoles as potent IDO1/TDO dual inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 6, 页码: 1087-1098
作者:
Yang, Lingling
;
Chen, Yang
;
He, Junlin
;
Njoya, Emmanuel Mfotie
;
Chen, Jianjun
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  |  
浏览/下载:10/0
  |  
提交时间:2021/11/04
Indoleamine 2,3-dioxygenase 1 (IDO1)
Tryptophan 2,3-dioxygenase (TDO)
1H-Indazoles
Dual inhibitor
Cancer immunotherapy
Antitumor activity
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