×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [6]
湖南大学 [6]
大连化学物理研究所 [3]
大连理工大学 [1]
长春光学精密机械与物... [1]
上海应用物理研究所 [1]
更多...
内容类型
期刊论文 [20]
发表日期
2019 [20]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共20条,第1-10条
帮助
限定条件
发表日期:2019
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23
作者:
Zou, Yi
;
Hu, Yue
;
Ge, Shushan
;
Zheng, Yingbo
;
Li, Yuezhen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
IDO1
Heme
T cell
Cancer immunotherapy
Virtual screening
Drug design
Molecular dynamics simulation
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:
Yang, Xiuyan
;
Deng, Meng
;
Zhang, Xi
;
Wang, Yi
;
Song, Kun
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/07/01
PI3K alpha inhibitors
proliferation inhibition
thieno[3
2-d]pyrimidine derivatives
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:
Chen, Deheng
;
Lu, Tian
;
Yan, Ziqin
;
Lu, Wenchao
;
Lyu, Xilin
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Bromodomain
BET protein
BD2
Selective
Crystal structure
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:
Wang, Zhenkang
;
Ma, Chunhua
;
Wang, Yujie
;
Xiao, Qiang
;
Xu, Chenghui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Gentisides
Neurotrophic activity
Isosteric replacement
Conformational restriction
PC 12 cells
Isolation and bioactive evaluation of flavonoid glycosides from Lobelia chinensis Lour using two-dimensional liquid chromatography combined with label-free cell phenotypic assays
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1601, 页码: 224-231
作者:
Wang, Jixia
;
Chen, Linlin
;
Qu, Lala
;
Li, Kuiyong
;
Zhao, Yaopeng
收藏
  |  
浏览/下载:274/0
  |  
提交时间:2019/12/02
Flavonoid glycosides
Separation and purification
G protein-coupled receptor 35
Two-dimensional liquid chromatography
Label-free cell phenotypic assays
Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 20, 页码: 6678-6682
作者:
Guan, Dongliang
;
Chen, Feifei
;
Qiu, Yunguang
;
Jiang, Bofeng
;
Gong, Likun
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
antibacterial
multidrug-resistant bacteria
sulfonium
vancomycin
Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1373-1384
作者:
Chai, Hao
;
Cheng, Xi
;
Zhou, Bin
;
Zhao, Lifen
;
Lin, Xianhua
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Positive Effects of Isopropanol as a Co-Precipitant in Glycerol-3-Phosphate Acyltransferase Crystallization
期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2019, 卷号: 18, 期号: 1, 页码: 227-231
作者:
Liu, Yinghui
;
Xue, Song
;
Zhang, Yunxiu
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/06/20
isopropanol
polyethylene glycol (PEG)
optimization
glycerol-3-phosphate acyltransferase (GPAT)
crystallization
Positive effects of isopropanol as a co-precipitant in glycerol-3-phosphate acyltransferase crystallization
期刊论文
Journal of ocean university of china, 2019, 卷号: 18, 期号: 1, 页码: 227-231
作者:
Zhang, Yunxiu
;
Feng, Yanbin
;
Wang, Yayue
;
Liu, Yinghui
;
Cao, Xupeng
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/05/08
Isopropanol
Polyethylene glycol (peg)
Optimization
Glycerol-3-phosphate acyltransferase (gpat)
Crystallization
An Optimization Strategy for High Efficiency and Low Axial Load Design of Hydraulic Model for Nuclear Reactor Coolant Pump [一种核主泵水力模型高效低轴向载荷优化改型策略]
期刊论文
Hedongli Gongcheng/Nuclear Power Engineering, 2019, 卷号: 40, 页码: 42-48
作者:
Lu, Y.
;
Wang, X.
;
Zhou, F.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/02
Axial loads
Coolants
Efficiency
Hydraulic models
Nuclear reactors
Pumps
Radial basis function networks
Structural optimization, High performance
Load characteristics
Nuclear reactor coolant pumps
Optimal structures
Optimization strategy
Performance characteristics
Radial basis function neural networks
Reactor coolant pumps, Structural design
©版权所有 ©2017 CSpace - Powered by
CSpace