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上海药物研究所 [9]
昆明植物研究所 [9]
山东大学 [6]
大连化学物理研究所 [5]
武汉大学 [5]
昆明医科大学 [5]
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期刊论文 [99]
学位论文 [2]
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2019 [101]
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Pharmacolo... [1]
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Commiphorines A and B, unprecedented sesquiterpenoid dimers from Resina Commiphora with striking activities on anti-inflammation and lipogenesis inhibition
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 23, 页码: 3825-3833
作者:
Dong, Lu
;
Qin, Da-Peng
;
Di, Qian-Qian
;
Liu, Ying
;
Chen, Wei-Lin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/03/17
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:
Chen, Deheng
;
Lu, Tian
;
Yan, Ziqin
;
Lu, Wenchao
;
Lyu, Xilin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Bromodomain
BET protein
BD2
Selective
Crystal structure
Discovery of dihydrooxazolo[2,3-a]isoquinoliniums as highly specific inhibitors of hCE2
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 61, 页码: 35904-35912
作者:
Ding, Lixia
;
Wang, Lu
;
Zou, Kun
;
Li, Bo
;
Song, Yunqing
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
A microfluidic strategy to fabricate ultra-thin polyelectrolyte hollow microfibers as 3D cellular carriers
期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 卷号: 104, 页码: 10
作者:
Liu, Hui
;
Wang, Yaqing
;
Chen, Wenwen
;
Yu, Yue
;
Jiang, Lei
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/12/02
Microfluidics
Alginate
Chitosan
Ultra-thin polyelectrolyte microfibers
Cell culture
Simple fabrication of inner chitosan-coated alginate hollow microfiber with higher stability
期刊论文
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2019, 卷号: 107, 期号: 8, 页码: 2527-2536
作者:
Liu, Hui
;
Wang, Yaqing
;
Yu, Yue
;
Chen, Wenwen
;
Jiang, Lei
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  |  
浏览/下载:76/0
  |  
提交时间:2019/12/02
microfluidics
alginate microfibers
chitosan coating
microfiber stability
cell culture
PD-L1 expression levels on tumor cells affect their immunosuppressive activity
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407
作者:
Zheng, Yang
;
Fang, You-Chen
;
Li, Jing
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
programmed cell death 1
programmed death-ligand 1
co-culture
immunosuppression
signaling pathway
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
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  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis
期刊论文
LIPIDS IN HEALTH AND DISEASE, 2019, 卷号: 18, 期号: 1, 页码: 11
作者:
Yang, Rui-Xu
;
Pan, Qin
;
Liu, Xiao-Lin
;
Zhou, Da
;
Xin, Feng-Zhi
收藏
  |  
浏览/下载:143/0
  |  
提交时间:2019/12/02
Ceramides
Autophagy
High fat diet
Non-alcoholic fatty liver disease
Targeted photoswitchable imaging of intracellular glutathione by a photochromic glycosheet sensor
期刊论文
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 15, 页码: 2380-2389
作者:
Chai, Xianzhi
;
Han, Hai-Hao
;
Zang, Yi
;
Li, Jia
;
He, Xiao-Peng
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/07/01
intracellular GSH
molecular switches
photochromic glycosheet
photoswitchable imaging
2D MnO2 nanosheets
Comparing the disrupting effects of short-, medium- and long-chain chlorinated Paraffins on cell viability and metabolism
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 685, 页码: 297-307
作者:
Ren, Xiaoqian
;
Geng, Ningbo
;
Zhang, Haijun
;
Wang, Feidi
;
Gong, Yufeng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/12/02
Chlorinated paraffins
HepG2 cell
Cytotoxicity
Metabolomics
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