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科研机构
上海药物研究所 [6]
山东大学 [2]
湖南大学 [2]
江苏大学 [1]
武汉轻工大学 [1]
武汉大学 [1]
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期刊论文 [14]
发表日期
2019 [14]
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Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:
Wang, Jubo
;
Li, Tinghan
;
Zhao, Tengteng
;
Wu, Tizhi
;
Liu, Chuang
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Wogonin
CDK9
AML
Flavonoid
Antitumor
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models
期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:
Long, Fei
;
He, Ye
;
Fu, Haoyu
;
Li, Yun
;
Bao, Xubin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
breast cancer
CDK 4/6
drug resistance
palbociclib
SHR6390
CDK4/6 inhibitor protects against myocardial cells apoptosis by inhibiting RB phosphorylation in H9c2 cells
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 509, 期号: 4
作者:
Li, Jing
;
Liu, Quan
;
Wang, Zhenggui
;
Wang, Yonggang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Palbociclib
High glucose
Cell cycle
ROS generation
Apoptosis
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 112
作者:
Xiong, Yudi
;
Li, Tianqi
;
Assani, Ganiou
;
Ling, Huan
;
Zhou, Qian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Cervical cancer
CDK4
CDK6
Ribociclib
Cell cycle
Cell apoptosis
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, in vitro and in human tumor xenograft models.
期刊论文
Cancer science, 2019
作者:
Fei Long
;
Ye He
;
Haoyu Fu
;
Yun Li
;
Xubin Bao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/17
CDK
4/6
SHR6390
breast
cancer
drug
resistance
palbociclib
CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia
期刊论文
INVESTIGATIONAL NEW DRUGS, 2019, 卷号: 37, 期号: 4, 页码: 625-635
作者:
Rahaman, Muhammed H.
;
Yu, Yingyi
;
Zhong, Longjin
;
Adams, Julian
;
Lam, Frankie
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
CDKI-73
CDK9
AML
MLL-AML
MV4-11 xenograft
Apoptosis
Cyclin-Dependent Kinase Inhibitor 3 Promoted Cell Proliferation by Driving Cell Cycle from G1 to S Phase in Esophageal Squamous Cell Carcinoma
期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 8, 页码: 1915-1922
作者:
Liu, Juan
;
Min, Li
;
Zhu, Shengtao
;
Guo, Qingdong
;
Li, Hengcun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
ESCC
CDKN3
cell cycle
G1/S transition
cyclinD-CDK4 complex
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: Vol.112, 页码: 108602
作者:
Yudi Xiong
;
Tianqi Li
;
Ganiou Assani
;
Huan Ling
;
Qian Zhou
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
CDK4
CDK6
Cell
apoptosis
Cell
cycle
Cervical
cancer
Ribociclib
Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-kappa B Activation and PD-L1 Expression
期刊论文
MOLECULAR CELL, 2019, 卷号: 73, 期号: 1, 页码: 22-+
作者:
Jin, Xin[1]
;
Ding, Donglin[2]
;
Yan, Yuqian[3]
;
Li, Hui[4]
;
Wang, Bo[5]
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/24
CDK4/6 inhibitor
CHD1
MAP3K7
NF-κB
PD-L1
RB
immunotherapy
phosphorylation
prostate cancer
radiotherapy
Design of Tat-Activated Cdk9 Inhibitor
期刊论文
International Journal of Peptide Research and Therapeutics, 2019, 卷号: 25, 期号: 2, 页码: 807-817
作者:
Zhao, Yunjie
;
Chen, Hao
;
Du, Chenghang
;
Jian, Yiren
;
Li, Haotian
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
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