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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease 期刊论文 PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14 作者:  Zhang, Yu;  Wu, Qimei;  Zhang, Lei;  Wang, Qing;  Yang, Zexian 收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Caffeic acid  A53T  Parkinson's disease  Autophagy  JNK   Neuroprotective Effect of Natural Alkaloid Fangchinoline Against Oxidative Glutamate Toxicity: Involvement of Keap1-Nrf2 Axis Regulation 期刊论文 CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1177-1186 作者:  Bao, Fengxia;  Tao, Lingxue;  Zhang, Haiyan 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Fangchinoline  Keap1  Nrf2  Oxidative stress   Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393 作者:  Cui, Xue;  Guo, Yu-e;  Fang, Jia-hui;  Shi, Chang-jie;  Suo, Na 收藏  |  浏览/下载：70/0  |  提交时间：2020/07/01 donepezil  aricept  oligodendrocyte  oligodendrocyte progenitor cell  differentiation  myelin sheaths  remyelination  CNS demyelinating disorders  multiple sclerosis   High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice 期刊论文 NATIONAL SCIENCE REVIEW, 2019, 卷号: 6, 期号: 6, 页码: 1223-1238 作者:  Zhang, Xiaochuan;  Yin, Xianzhen;  Zhang, Jingjing;  Li, Anan;  Gong, Hui 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Micro-Optical Sectioning Tomography  image optimization  Alzheimer's disease  impaired hippocampal vasculature  virtual vascular endoscopy   Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei 收藏  |  浏览/下载：116/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression 期刊论文 CELL RESEARCH, 2019, 卷号: 29, 期号: 10, 页码: 787-803 作者:  Wang, Xinyi;  Sun, Guangqiang;  Feng, Teng;  Zhang, Jing;  Huang, Xun 收藏  |  浏览/下载：70/0  |  提交时间：2020/07/01 Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268 作者:  Liu, Xia;  Wang, Wei;  Chen, Hua-li;  Zhang, Hai-yan;  Zhang, Nai-xia 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 Alzheimer's disease  type 2 diabetes  APP/PS1 transgenic mice  metabolomics  NMR  glucose metabolism dysfunctions   Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291 作者:  Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Alzheimer's disease  nitazoxanide  autophagy  inflammation  APP/PS1 transgenic mice   Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives 期刊论文 MOLECULES, 2019, 卷号: 24, 期号: 16, 页码: 20 作者:  Huang, Xing;  Li, Ning;  Pu, Yiqiong;  Zhang, Tong;  Wang, Bing 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 neuroprotective effects  ginseng  Alzheimer's disease  ginsenoside  Parkinson's disease   Sensors, Imaging Agents, and Theranostics to Help Understand and Treat Reactive Oxygen Species Related Diseases 期刊论文 SMALL METHODS, 2019, 卷号: 3, 期号: 7, 页码: 42 作者:  Yon, Kai-Cheng;  Sedgwick, Adam C.;  Zang, Yi;  Chen, Guo-Rong;  He, Xiao-Peng 收藏  |  浏览/下载：66/0  |  提交时间：2020/07/01 fluorescence  imaging agents  ROS  sensors  theranostics