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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文 BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33 作者:  Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue 收藏  |  浏览/下载：47/0  |  提交时间：2018/10/11 Huntington's Disease  Polyglutamine  Intravenous Immunoglobulin  Huntingtin Protein   Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文 BRAIN, 2018, 卷号: 141, 页码: 1782-1798 作者:  Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua 收藏  |  浏览/下载：52/0  |  提交时间：2019/01/08 GPCR  target validation  polyQ  neurodegeneration  antagonists   PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin 期刊论文 FASEB JOURNAL, 2018, 卷号: 32, 期号: 6 作者:  Yang, Hui;  Yue, Hong-Wei;  He, Wen-Tian;  Hong, Jun-Ye;  Jiang, Lei-Lei 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05 neurodegeneration  inclusions  interaction  pathologic mechanism   HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease 期刊论文 AUTOPHAGY, 2018, 卷号: 14, 期号: 1 作者:  Fu, Yuhua;  Sun, Xiaoli;  Lu, Boxun 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/05 DAXX  feedback  kinase  neurodegeneration  polyQ   Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文 BRAIN, 2018, 卷号: 141 作者:  Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua 收藏  |  浏览/下载：29/0  |  提交时间：2019/12/05 GPCR  target validation  polyQ  neurodegeneration  antagonists   PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin 期刊论文 FASEB JOURNAL, 2018, 卷号: 32, 期号: 6, 页码: 2923-2933 作者:  Yang, Hui;  Yue, Hong-Wei;  He, Wen-Tian;  Hong, Jun-Ye;  Jiang, Lei-Lei 收藏  |  浏览/下载：26/0  |  提交时间：2019/04/28 Protein-quality Control  Group-c Protein  Polyglutamine Disease  Alpha-synuclein  Neurodegenerative Diseases  Parkinsons-disease  Nuclear Inclusions  Nucleocytoplasmic Transport  Deubiquitinating Function  Cytoplasmic Inclusions