CORC

浏览/检索结果: 共121条,第1-10条 帮助

限定条件    
已选(0)清除 条数/页:   排序方式:
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/11
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection 期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 138, 期号: 4, 页码: 247-256
作者:  Yao, Xingang;  Guo, Songxin;  Wu, Wenyu;  Wang, Jinan;  Wu, Shengen
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 6, 页码: 1998-2008
作者:  Zhong, Li;  Liu, Qing;  Ting, Yan Sie;  Vun Yien Thien;  Kalong, Nurwafa Syafiqah Binti
收藏  |  浏览/下载:89/0  |  提交时间:2019/01/08
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
收藏  |  浏览/下载:108/0  |  提交时间:2019/01/08
Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9177-9204
作者:  Li, Daqiang;  Zhang, Xiaotuan;  Ma, Xiaodong;  Xu, Lei;  Yu, Jianjun
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Characterization of Solid-State Drug Polymorphs and Real-Time Evaluation of Crystallization Process Consistency by Near-Infrared Spectroscopy 期刊论文
FRONTIERS IN CHEMISTRY, 2018, 卷号: 6, 页码: 7
作者:  Qi, Shu-Ye;  Tian, Ye;  Zou, Wen-Bo;  Hu, Chang-Qin
收藏  |  浏览/下载:51/0  |  提交时间:2018/12/04
Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Su, Haixia;  Xu, Yechun
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08


©版权所有 ©2017 CSpace - Powered by CSpace