QQ客服 官方微博 反馈留言

浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identification of a cellularly active SIRT6 allosteric activator 期刊论文 NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+ 作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin 收藏  |  浏览/下载：88/0  |  提交时间：2019/01/08 Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming 收藏  |  浏览/下载：65/0  |  提交时间：2019/12/25 CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia   Design, synthesis, and molecular docking study of 3H-imidazole[4,5-c]pyridine derivatives as CDK2 inhibitors 期刊论文 ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 6 作者:  Wu, Yi-Zhe;  Ying, Hua-Zhou;  Xu, Lei;  Cheng, Gang;  Chen, Jing 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 cancer  CDK2 inhibitor  imidazo[4  5-c]pyridine  targeted therapy   Selective and novel cyclin-dependent kinases 4 inhibitor: synthesis and biological evaluation 期刊论文 Medicinal Chemistry Research, 2018, 卷号: Vol.27 No.6, 页码: 1666-1678 作者:  Qingxiang Guo;  Yongtao Li;  Chao Zhang;  Zhi Huang;  Xin Wang 收藏  |  浏览/下载：7/0  |  提交时间：2019/02/25 Progress of CDK4/6 Inhibitor Palbociclib in the Treatment of Cancer 期刊论文 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 卷号: 18, 期号: 9, 页码: 1241-1251 作者:  Chen, Fengquan;  Liu, Chunxi;  Zhang, Jian;  Xu, Wenfang;  Zhang, Yingjie 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Cyclin-Dependent Kinases (CDKs)  palbociclib  monotherapy  combined  therapy  anti-cancer  cell cycle arrest