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上海药物研究所 [60]
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期刊论文 [387]
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Revealing transcription factor and histone modification co-localization and dynamics across cell lines by integrating ChIP-seq and RNA-seq data
期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 16
作者:
Zhang, Lirong
;
Xue, Gaogao
;
Liu, Junjie
;
Li, Qianzhong
;
Wang, Yong
收藏
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浏览/下载:223/0
  |  
提交时间:2019/01/11
Transcription factor
Histone modification
Co-localization
Dynamics
Higher Accuracy Achieved in the Simulations of Protein Structure Refinement, Protein Folding, and Intrinsically Disordered Proteins Using Polarizable Force Fields
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 24, 页码: 7110-7116
作者:
Wang, Anhui
;
Li, Guohui
;
Zhang, Zhichao
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  |  
浏览/下载:24/0
  |  
提交时间:2019/06/20
Higher accuracy achieved in the simulations of protein structure refinement, protein folding, and intrinsically disordered proteins using polarizable force fields
期刊论文
Journal of physical chemistry letters, 2018, 卷号: 9, 期号: 24, 页码: 7110-7116
作者:
Wang, Anhui
;
Zhang, Zhichao
;
Li, Guohui
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  |  
浏览/下载:43/0
  |  
提交时间:2019/05/08
Solution structure of TbCentrin4 from Trypanosoma brucei and its interactions with Ca2+ and other centrins
期刊论文
BIOCHEMICAL JOURNAL, 2018, 卷号: 475, 页码: 3763-3778
作者:
Shan, Fangzhen
;
Ye, Kaiqin
;
Zhang, Jiahai
;
Liao, Shanhui
;
Zhang, Xuecheng
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  |  
浏览/下载:101/0
  |  
提交时间:2019/12/25
Effect of Pore Structure on Protein Capacity in Macroporous Polymer Chromatographic Supports
期刊论文
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2018, 卷号: 39, 期号: 12, 页码: 2673-2678
作者:
Li Heng
;
Wang Shaoyun
;
Fang Jiaxuan
;
Zhao Lan
;
Jin Haibo
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  |  
浏览/下载:57/0
  |  
提交时间:2019/04/03
Macroporous Polymer Microsphere
Chromatographic Media
Protein Capactiy
High Through-put
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
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  |  
浏览/下载:56/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Transcriptome from Pacific cod liver reveals types of apolipoproteins and expression analysis of AFP-IV, structural analogue with mammalian ApoA-I
期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2018, 卷号: 28, 页码: 204-212
作者:
Mao, Ming-Guang
;
Chen, Yu
;
Liu, Rui-Ting
;
Lu, Hui-Qian
;
Gu, Jie
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  |  
浏览/下载:61/0
  |  
提交时间:2019/07/01
Apolipoprotein
Gadus macrocephalus
Type-IV antifreeze protein
ApoA-I homolog
Transcriptome
Beyond the Roles in Biomimetic Chemistry: An Insight into the Intrinsic Catalytic Activity of an Enzyme for Tumor-Selective Phototheranostics
期刊论文
ACS NANO, 2018, 卷号: 12, 期号: 12, 页码: 12169-12180
作者:
Zhang, Bingbo
;
Zhou, Xin
;
Chen, Shizhen
;
Yao, Defan
;
Shi, Yuxin
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  |  
浏览/下载:43/0
  |  
提交时间:2019/06/24
biomimetic synthesis
protein activity
catalytic nanomedicine
MR/PA imaging
photothermal therapy
The protective role of glutamine on enteropathy induced by high dose of soybean meal in turbot, Scophthalmus maximus L.
期刊论文
AQUACULTURE, 2018, 卷号: 497, 期号: 1, 页码: 510-519
作者:
Liu, Yang
;
Chen, Zhichu
;
Dai, Jihong
;
Yang, Pei
;
Hu, Haibin
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  |  
浏览/下载:47/0
  |  
提交时间:2019/07/02
Glutamine
Soybean meal
Enteropathy
Intestinal mucosal barrier
Intestinal microbiota
Turbot
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