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科研机构
上海药物研究所 [11]
复旦大学上海医学院 [3]
山东大学 [1]
湖南大学 [1]
内容类型
期刊论文 [16]
发表日期
2018 [16]
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Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa
期刊论文
CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 11
作者:
Wang, Xiao-Hang
;
Zhu, Ke-Xin
;
Li, Jing-Ya
;
Lei, Chun
;
Hou, Ai-Jun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Dodonaea viscosa
vistriterpenoids A and B
triterpenoids
protein tyrosine phosphatase 1b (PTP1B)
PTP1B inhibitors
inhibitory activity
Dictyoptesterols A-C, Delta(22)-24-oxo cholestane-type sterols with potent PTP1B inhibitory activity from the brown alga Dictyopteris undulata Holmes
期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 241-246
作者:
Yang, Fei
;
Zhang, Liang-Wei
;
Feng, Mei-Tang
;
Liu, Ai-Hong
;
Li, Jia
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Dictyotaceae
Dictyopteris undulate
Cholestane-type sterols
Dictyoptesterols A-C
Protein tyrosine phosphatase-1B inhibitors
High-throughput screening for small molecule inhibitors of the type-I interferon signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 6, 页码: 889-899
作者:
Yuliantie, Elita
;
Dai, Xinchuan
;
Yang, Dehua
;
Crack, Peter J.
;
Wang, Ming-Wei
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
High-throughput screening
Interferon alpha receptor
Secreted embryonic alka-line phosphatase
JAK-STAT
IFN regulatory factor
Inhibitor
Synthesis and Cell Division Cycle 25B Phosphatase/Protein Tyrosine Phosphatase 1B Inhibitory Activity Evaluation of Novel Acylthiourea Derivatives
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 5, 页码: 1242-1250
作者:
Li Yingjun
;
Wang Siyuan
;
Jin Kun
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
acylthiourea
carbazole
synthesis
Cdc25B and PTP1B inhibitors
molecular docking
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:
Ma, Fei
;
Liu, Jian
;
Zhou, Tingting
;
Lei, Min
;
Chen, Jing
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
Thienol2,3-b]pyridine derivatives
Structure-activity relationships (SARs)
Hepatic gluconeogenesis
Type 2 diabetes mellitus (T2DM)
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xie, Wei
;
Ye, Yangliang
;
Feng, Ying
;
Xu, Tifei
;
Huang, Suling
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  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
cAMP
gluconeogenesis
linderane
phosphodiesterase
type 2 diabetes
Further New Diterpenoids as PTP1B Inhibitors from the Xisha Soft Coral Sinularia polydactyla
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 4
作者:
Ye, Fei
;
Zhu, Zheng-Dan
;
Gu, Yu-Cheng
;
Li, Jia
;
Zhu, Wei-Liang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Sinularia polydactyla
diterpenoids
PTP1B inhibitory activity
Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 3
作者:
Liu, Jin
;
Chen, Yu
;
Li, Jing-Ya
;
Luo, Cheng
;
Li, Jia
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
phidianidine
marine natural products
PTP1B inhibitor
specific selectivity
docking analysis
Function Oriented Synthesis
structure-activity relationship
Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression
期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 3, 页码: 821-831
作者:
Wang, Yu-Ting
;
Yuan, Bo
;
Chen, Hua-Dong
;
Xu, Lin
;
Tian, Yu-Nan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
53BP1
acquired resistance
phosphatase and tensin homolog deficiency
poly(ADP-ribose) polymerase inhibitors
SAMHD1
Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 692-700
作者:
Du, Yongli
;
Zhang, Yanhui
;
Ling, Hao
;
Li, Qunyi
;
Shen, Jingkang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Protein tyrosine phosphatase 1B inhibitors
N-(2,5-diethoxy-phenyl)-methane sulfonamide
Type 2 diabetes mellitus
PTP1B
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