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科研机构
上海药物研究所 [13]
复旦大学上海医学院 [10]
四川大学 [6]
武汉大学 [5]
湖南大学 [5]
山东大学 [4]
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期刊论文 [80]
会议论文 [2]
发表日期
2018 [82]
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A new class of HIV-1 inhibitors and the target identification via proteomic profiling
期刊论文
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 1430-1439
作者:
Ge, Ying-Zi
;
Zhou, Bin
;
Xiao, Ruo-Xuan
;
Yuan, Xiao-Jing
;
Zhou, Hu
收藏
  |  
浏览/下载:185/0
  |  
提交时间:2019/01/08
ergostane-type steroids
anti-HIV
target identification
PKM2
Characterization of Bacterial Communities and Their Antibiotic Resistance Profiles in Wastewaters Obtained from Pharmaceutical Facilities in Lagos and Ogun States, Nigeria
期刊论文
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2018, 卷号: 15, 期号: 7, 页码: -
作者:
Yang, Min
;
Ogunjobi, Adeniyi
;
Ibekwe, Mark
;
Obayiuwana, Amarachukwu
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/06/21
pharmaceutical wastewater
antibiotics-resistant bacteria (ARB)
antibiotic-resistance genes (ARG)
sulfonamide resistance genes
mobile genetic elements
Improved synthesis of YT-14, a potent antibiotic to multidrug-resistant strains
期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2018, 期号: 7, 页码: 354-360
作者:
Wei, Jianhai
;
Kong, Deyu
;
Wang, Lei
;
Zhang, Yinyong
;
Hu, Wenhao
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
drug candidate
YT-14
multidrug resistant
Gram-negative bacteria
The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 10, 页码: 1943-1948
作者:
Zhang, Wen-Ming
;
Yao, Yang
;
Yang, Teng
;
Wang, Xue-Ying
;
Zhu, Zhen-Yun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Antistaphylococcal
Multidrug-resistant
Synthesis
Oxime
Dehydroabietic acid
Design, synthesis and biological evaluation of C(4) substituted monobactams as antibacterial agents against multidrug-resistant Gram-negative bacteria
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 98-109
作者:
Kou, Qunhuan
;
Wang, Ting
;
Zou, Feng
;
Zhang, Shuhua
;
Chen, Qian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Monobactam
C(4) substituents
Pyridone
MDR Gram-negative bacteria
Antibacterial activity
Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 5, 页码: 502-506
作者:
Guo, Yalan
;
Wang, Yujie
;
Li, Haihong
;
Wang, Ke
;
Wan, Qi
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Phenylsulfonylfuroxan
3-benzyl coumarin
anticancer
multidrug resistance
P-gp overexpression
Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis
期刊论文
MOLECULAR PHARMACEUTICS, 2018, 卷号: 15, 期号: 4, 页码: 1618-1626
作者:
Kang, Xuejia
;
Zheng, Zenin
;
Liu, Zehua
;
Wang, Huiyuan
;
Zhao, Yuge
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
cell-penetrating peptide
doxorubicin
andrographolide
liposome
angiogenesis
breast cancer
Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 233-237
作者:
Ni, Shuaishuai
;
Li, Baoli
;
Chen, Feifei
;
Wei, Hanwen
;
Mao, Fei
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Virulence factor
pigment
multidrug resistant MRSA
CrtN inhibitor
Characteristics of ARG-carrying plasmidome in the cultivable microbial community from wastewater treatment system under high oxytetracycline concentration
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 卷号: 102, 期号: 4, 页码: 1847-1858
作者:
Shi, Yanhong
;
Zhang, Yu
;
Yang, Min
;
Tian, Zhe
;
Zhang, Hong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/06/21
Antibiotic resistance genes
Plasmids
Metagenomic sequencing
High antibiotic concentration
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 224-250
作者:
Li, Baoli
;
Ni, Shuaishuai
;
Mao, Fei
;
Chen, Feifei
;
Liu, Yifu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
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