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Reconsideration of Anticholinesterase Therapeutic Strategies against Alzheimer's Disease 期刊论文
ACS chemical neuroscience, 2018
作者:  Wang, Huan;  Zhang, Haiyan
收藏  |  浏览/下载:59/0  |  提交时间:2019/01/08
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors 期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:  Cheng, Zhi-Qiang;  Zhu, Kong-Kai;  Zhang, Juan;  Song, Jia-Li;  Muehlmann, Luis Alexandre
收藏  |  浏览/下载:49/0  |  提交时间:2019/01/08
Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents 期刊论文
ACS chemical neuroscience, 2018
作者:  Xu, Yixiang;  Zhang, Jian;  Wang, Huan;  Mao, Fei;  Bao, Keting
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08
Acetylcholinesterase Is a Potential Biomarker for a Broad Spectrum of Organic Environmental Pollutants 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 卷号: 52, 期号: 15, 页码: 8065-8074
作者:  Fu, Hualing;  Xia, Yingjie;  Chen, Yangshen;  Xu, Tuan;  Xu, Li
收藏  |  浏览/下载:33/0  |  提交时间:2019/06/20
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:  Liu, Wenwen;  Wang, Huan;  Li, Xiaokang;  Xu, Yixiang;  Zhang, Jian
收藏  |  浏览/下载:40/0  |  提交时间:2019/01/08
Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetyicholinesterase (AChE) and Phosphodiesterase 5 (PDE5) 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 7, 页码: 1625-1636
作者:  Ni, Wei;  Wang, Huan;  Li, Xiaokang;  Zheng, Xinyu;  Wang, Manjiong
收藏  |  浏览/下载:44/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08
Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 76, 期号: 2, 页码: 400-414
作者:  Jiang, YY (Jiang, Yingying);  Gao, HW (Gao, Hongwei);  Gao, HW
收藏  |  浏览/下载:32/0  |  提交时间:2018/03/14
Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and beta-amyloid aggregation inhibitory activities as potential agents against Alzheimer\'s disease 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: Vol.26 No.8, 页码: 1885-1895
作者:  Xu, R;  Xiao, GY;  Li, Y;  Liu, HY;  Song, Q
收藏  |  浏览/下载:3/0  |  提交时间:2019/02/25
Novel salicylamide derivatives as potent multifunctional agents for the treatment of Alzheimer's disease: Design, synthesis and biological evaluation. 期刊论文
Bioorganic chemistry, 2018, 卷号: Vol.84, 页码: 137-149
作者:  Song Qing;  Li Yan;  Cao Zhongcheng;  Qiang Xiaoming;  Tan Zhenghuai
收藏  |  浏览/下载:4/0  |  提交时间:2019/02/25


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