QQ客服 官方微博 反馈留言

浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81 作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11 ABL kinase  Kinase inhibitor  ABL mutant  CML   Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384 作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E. 收藏  |  浏览/下载：62/0  |  提交时间：2019/06/10 PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL   Comparison of Frequency and Sensitivity of BCR-ABL1 Kinase Domain Mutations in Asian and White Patients With Imatinib-resistant Chronice-Phase Chronic Myeloid Leukemia 期刊论文 CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 卷号: 18, 期号: 10 作者:  Cui, Jiu Wei;  Kim, Hawk;  Kim, SooHyun;  Kim, Hyeoung-Joon;  Kim, Yeo-Kyeoung 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/05 Asian countries  BCR-ABL1 mutation  CML  Drug resistance  Imatinib   Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.160, 页码: 61-81 作者:  Liu, Xiaochuan;  Wang, Beilei;  Wang, Junjie;  Zhang, Yicong;  Jiang, Zongru 收藏  |  浏览/下载：12/0  |  提交时间：2019/04/24 ABL kinase  Kinase inhibitor  ABL mutant  CML   A tightly controlled Src-YAP signaling axis determines therapeutic response to dasatinib in renal cell carcinoma 期刊论文 THERANOSTICS, 2018, 卷号: 8, 期号: 12, 页码: 3256-3267 作者:  Sun, Jingya;  Wang, Xin;  Tang, Boyun;  Liu, Hongchun;  Zhang, Minmin 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 dasatinib  YAP  Src  renal cell carcinoma