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浏览/检索结果: 共43条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests 期刊论文 Mutagenesis, 2018 作者:  Liu, Weiying;  Xi, Jing;  Cao, Yiyi;  You, Xinyue;  Chen, Ruixue 收藏  |  浏览/下载：97/0  |  提交时间：2019/01/08 Heme oxygenase-1 as a potential therapeutic target in rheumatic diseases 期刊论文 Life sciences, 2018 作者:  Liu, Yu-Ting;  Lin, Ze-Min;  He, Shi-Jun;  Zuo, Jian-Ping 收藏  |  浏览/下载：86/0  |  提交时间：2019/01/08 Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699 作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi 收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08 Pharmacophore combination  Isoquinoline  PRMT5 inhibitor  Molecular docking  Molecular dynamics simulation   beta-Galactosidase BMG without galactose and glucose inhibition: Secretory expression in Bacillus subtilis and for synthesis of oligosaccharide 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 120, 页码: 274-278 作者:  Zhao, Lu;  Zhou, Youzhi;  Qin, Song;  Qin, Panpan;  Chu, Jianlin 收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 beta-Galactosidase  Extracellular expression  Galacto-oligosaccharides synthesis   Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations 期刊论文 BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298 作者:  Zhu, Kongkai;  Tao, Hongrui;  Song, Jia-Li;  Jin, Lu;  Zhang, Yuanyuan 收藏  |  浏览/下载：129/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Arginine methylation  Virtual screening  Molecular docking  Molecular dynamics simulation   A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing 期刊论文 CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74 作者:  Zhou, Lishuang;  Liao, Wenfeng;  Zeng, Hui;  Yao, Yanli;  Chen, Xia 收藏  |  浏览/下载：152/0  |  提交时间：2019/01/08 Lycium barbarum L.  Pectin  A beta(42)  Alzheimer's disease  Amyloid precursor protein processing   The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine 期刊论文 MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52 作者:  Li, Hong;  Zhao, Lihua;  Singh, Rani;  Ham, J. Nina;  Fadoju, Doris O. 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 Glucagon receptor  Newborn screening  GCGR mutation  Hyperaminoacidemia  Mahvash disease  Pancreatic alpha cell hyperplasia (ACH)  Pancreatic neuroendocrine tumor (PNET)   Caryopincaolide M, a rearranged abietane diterpenoid with new skeleton and a new iridoid from Caryopteris incana 期刊论文 Journal of natural medicines, 2018 作者:  Zhang, Cheng-Gang;  Chen, Ting;  Mao, Xu-Dong;  Zhao, Sen-Miao;  Chou, Gui-Xin 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN 期刊论文 NATURE COMMUNICATIONS, 2018, 卷号: 9 作者:  Liu, Bin;  Jiang, Shangwen;  Li, Min;  Xiong, Xuelian;  Zhu, Mingrui 收藏  |  浏览/下载：109/0  |  提交时间：2019/01/08 Elucidation of lid open and orientation of lipase activated in interfacial activation by amphiphilic environment 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 119, 页码: 1211-1217 作者:  Cheng, Cheng;  Jiang, Tianyue;  Wu, Yulu;  Cui, Lupeng;  Qin, Song 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Lipase  Amphiphilic media  Interfacial activation