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浏览/检索结果: 共38条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases 期刊论文 Drug metabolism and disposition: the biological fate of chemicals, 2018 作者:  Kong, Fandi;  Pang, Xiaoyan;  Zhao, Jihui;  Deng, Pan;  Zheng, Mingyue 收藏  |  浏览/下载：82/0  |  提交时间：2019/01/08 Age-associated changes in GSH S-transferase gene/proteins in livers of rats 期刊论文 Redox report : communications in free radical research, 2018, 卷号: 23, 期号: 1, 页码: 213-218 作者:  Xu, Shangfu;  Hou, Dongshun;  Liu, Jie;  Ji, Lili 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine 期刊论文 MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52 作者:  Li, Hong;  Zhao, Lihua;  Singh, Rani;  Ham, J. Nina;  Fadoju, Doris O. 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 Glucagon receptor  Newborn screening  GCGR mutation  Hyperaminoacidemia  Mahvash disease  Pancreatic alpha cell hyperplasia (ACH)  Pancreatic neuroendocrine tumor (PNET)   High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822 作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree 收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08 high throughput screening  PI3 kinase  PI3K alpha H1047R  inhibitors  molecular modeling   Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein 期刊论文 Acta pharmacologica Sinica, 2018 作者:  Meng, Jian;  Liu, Xiao-Yun;  Ma, Sheng;  Zhang, Hua;  Yu, Song-da 收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 Direct screening of malonylginsenosides from nine Ginseng extracts by an untargeted profiling strategy incorporating in-source collision-induced dissociation, mass tag, and neutral loss scan on a hybrid linear ion-trap/Orbitrap mass spectrometer coupled to ultra-high performance liquid chromatography 期刊论文 JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1571, 页码: 213-222 作者:  Shi, Xiaojian;  Yang, Wenzhi;  Huang, Yong;  Hou, Jinjun;  Qiu, Shi 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 In-source collision-induced dissociation  Mass tag  Linear ion-trap/Orbitrap  Mass spectrometry  Panax  Malonylginsenoside  Untargeted profiling   Artificial intelligence in drug design 期刊论文 SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204 作者:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 drug design  artificial intelligence  deep learning  QSAR  ADME/T   Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503 作者:  Dong, Jiajia;  Olaleye, Olajide E.;  Jiang, Rongrong;  Li, Jing;  Lu, Chuang 收藏  |  浏览/下载：99/0  |  提交时间：2019/01/08 A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole and nanosilver 期刊论文 NANO RESEARCH, 2018, 卷号: 11, 期号: 9, 页码: 4507-4523 作者:  Liang, Jianming;  Li, Ruixiang;  He, Yuwei;  Ling, Chengli;  Wang, Qi 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 albendazole  nano silver  co-delivery  tumor targeting  energy metabolism   Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate 期刊论文 DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328 作者:  Hou, Xiangyu;  Zhou, Jialan;  Yu, Songda;  Zhou, Lei;  Zhang, Yifan 收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08