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CORC

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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery 期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:  Yin, Weimin;  Yu, Xiaolu;  Kang, Xuejia;  Zhao, Yuge;  Zhao, Pengfei
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology 期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18, 页码: 17
作者:  Bing, Zhitong;  Cheng, Zhiyuan;  Shi, Danfeng;  Liu, Xinkui;  Tian, Jinhui
收藏  |  浏览/下载：91/0  |  提交时间：2019/10/09
Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology 期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
作者:  Bing, Zhitong;  Cheng, Zhiyuan;  Shi, Danfeng;  Liu, Xinkui;  Tian, Jinhui
收藏  |  浏览/下载：74/0  |  提交时间：2019/03/27
Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy 期刊论文
MOLECULAR THERAPY, 2018, 卷号: 26, 期号: 10, 页码: 2456-2465
作者:  Sun, Yuxiang;  Dai, Hui;  Chen, Shaopeng;  Zhang, Yajun;  Wu, Tao
收藏  |  浏览/下载：35/0  |  提交时间：2019/12/25
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin
收藏  |  浏览/下载：177/0  |  提交时间：2019/01/08
New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis 期刊论文
CANCER LETTERS, 2018, 卷号: 416, 页码: 57-65
作者:  Xu, Lin;  Wang, Wei;  Meng, Tao;  Ma, Lan-Ping;  Tong, Lin-Jiang
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation 期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 2
作者:  Li, Junjie;  Qu, Xiaochao;  Tian, Jie;  Zhang, Jian-Ting;  Cheng, Ji-Xin
收藏  |  浏览/下载：26/0  |  提交时间：2018/10/10
Intelligent mos2 nanotheranostic for targeted and enzyme-/ph-/nir-responsive drug delivery to overcome cancer chemotherapy resistance guided by pet imaging 期刊论文
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 4, 页码: 4271-4284
作者:  Dong, Xinghua;  Yin, Wenyan;  Zhang, Xiao;  Zhu, Shuang;  He, Xiao
收藏  |  浏览/下载：68/0  |  提交时间：2019/04/23

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