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科研机构
大连化学物理研究所 [7]
暨南大学 [6]
华南理工大学 [2]
复旦大学上海医学院 [2]
大连理工大学 [1]
深圳先进技术研究院 [1]
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期刊论文 [22]
发表日期
2017 [22]
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Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1
期刊论文
ACTA PHARMACEUTICA SINICA B, 2017, 卷号: 7, 期号: 6, 页码: 657-664
作者:
Cheng, Xuewei
;
Lv, Xia
;
Qu, Hengyan
;
Li, Dandan
;
Hu, Mengmeng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/06/20
Icotinib
Erlotinib
Ugt1a1
Inhibitory Effects
Drug-drug Interacts (Ddis)
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Yang, Ling
;
Ge, Guang-Bo
;
Jarvinen, Erkka
;
Troberg, Johanna
;
Finel, Moshe
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Troberg, Johanna
;
Jarvinen, Erkka
;
Ge, Guang-Bo
;
Yang, Ling
;
Finel, Moshe
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites
期刊论文
XENOBIOTICA, 2017, 卷号: 47, 期号: 6, 页码: 498-504
作者:
Tu, Cai-Xia
;
Liang, Si-Cheng
;
Ge, Guang-Bo
;
Xia, Yang-Liu
;
Dong, Pei-Pei
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  |  
浏览/下载:20/0
  |  
提交时间:2017/10/29
Daphnetin
COMT inhibitor
8-O-methyldaphnetin
ligand-protein interaction
Phase II metabolite
structural modification
Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction
期刊论文
FITOTERAPIA, 2017, 卷号: 117, 页码: 118-125
作者:
Meng, Fanxing
;
Li, Yan
;
He, Guiyuan
;
Ge, Guangbo
;
Liu, Shumin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/06/20
Isofraxidin
Udp-glucuronosyltransferases (Ugts)
Human Liver Microsomes (Hlm)
Human Intestinal Microsomes (Him)
Species Differences
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:
Yang, Na
;
Sun, Run-Bin
;
Chen, Xing-Long
;
Zhen, Le
;
Ge, Chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2017/05/19
hyperglycemia
glucose-lowering effect
berberine
berberrubine
glucuronide
alpha-glycosidase
HFD-induced hyperglycemia model of C57BL/6 mice
human normal liver cell line L-O2
pharmacokinetics
N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification
期刊论文
Journal of Pharmaceutical and Biomedical Analysis, 2017
作者:
Danyi Lu
;
Baojian Wu
;
Qian Xie
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2018/02/02
IN VITRO CHARACTERIZATION OF THE GLUCURONIDATION PATHWAYS OF D-LUCIFERIN MEDIATED BY HUAMN UDP-GLUCURONOSYL-TRANSFERASES
期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2017, 卷号: 32, 期号: 1, 页码: S77-S77
作者:
Ge, Guang-Bo
;
Xia, Yangliu
;
Lv, Xia
;
He, Guiyuan
;
Dou, Tongyi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/06/20
Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 17
作者:
Li, Li
;
Hao, Miao
;
Xu, Ming-Cheng
;
Gu, Jing-Kai
;
Wang, Zai-Jie Jim
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
UGT2B7
BDNF
morphine tolerance
colorectal carcinoma
epigenetics
Potential Drug-drug Interaction between Dabrafenib and Insulin Secretagogue Repaglinide
期刊论文
LATIN AMERICAN JOURNAL OF PHARMACY, 2017, 卷号: 36, 期号: 8
作者:
Wang, Yong-Gang
;
Wang, Shu-Dong
;
Miao, Xiao
;
Liu, Quan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
cancer
dabrafenib
drug-drug interaction
glucuronidation
repaglinide
type 2 diabetes mellitus (T2DM)
UDP-glucuronosyltransferase (UGT) 1A1
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