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Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia
收藏  |  浏览/下载:60/0  |  提交时间:2019/01/08
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan
收藏  |  浏览/下载:710/0  |  提交时间:2018/08/17
Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Sun, Deheng;  Zhao, Zhenjiang
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) of Yunnan in southwestern China 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 9
作者:  Zhou, Yongchun;  Yang, Yanlong;  Yang, Chenggang;  Chen, Yunlan;  Yang, Changshao
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/04
Central nervous system progression in advanced non-small cell lung cancer patients with EGFR mutations in response to first-line treatment with two EGFR-TKIs, gefitinib and erlotinib: a comparative study 期刊论文
BMC CANCER, 2017, 卷号: 17
作者:  Yang, Zhen-Zhou;  Li, Meng-Xia;  He, Hao;  Ruan, Zhi-Hua;  Zhu, Yu-Xi
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/04
Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  Hu, Xiangxiang;  Shi, Si;  Wang, Huan;  Yu, Xiaochen;  Wang, Qian
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
High probability and frequency of EGFR mutations in non-small cell lung cancer with brain metastases 期刊论文
JOURNAL OF NEURO-ONCOLOGY, 2017, 卷号: 135, 期号: 2
作者:  Ge, Mengxi;  Zhuang, Yingjie;  Zhou, Xinli;  Huang, Ruofan;  Liang, Xiaohua
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05
Assessment of EGFR mutations in plasma from advanced NSCLC patients by modified cell-free DNA extraction method and blocker PCR assays 会议论文
作者:  Zhang, Meiling;  Gong, Ziying;  Li, Chun;  Hu, Jie;  Hong, Qunying
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05
The Prevalence and Genotype Distribution of Dual in Cis EGFR Mutations in Chinese Advanced Non-Small Cell Lung Cancer Patients 会议论文
作者:  Li, M.;  Zhou, C.;  Yang, J.;  Lu, S.;  Zheng, D.
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
Assessment of EGFR mutations in plasma from advanced NSCLC patients by modified cell-free DNA extraction method and blocker PCR assays. 期刊论文
Journal of Clinical Oncology, 2017, 卷号: 35
作者:  Zhang M., Gong Z., Li C., Hu J., Hong Q., Hou Y., Zhang D., Zhang X.
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05


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