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科研机构
上海药物研究所 [108]
内容类型
期刊论文 [108]
发表日期
2017 [108]
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共108条,第1-10条
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发表日期:2017
专题:上海药物研究所
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Theranostic Prodrug Vesicles for Reactive Oxygen Species-Triggered Ultrafast Drug Release and Local-Regional Therapy of Metastatic Triple-Negative Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 46
作者:
Zhou, Fangyuan
;
Feng, Bing
;
Wang, Tingting
;
Wang, Dangge
;
Cui, Zhirui
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/01/08
cancer theranostics
local-regional therapy
prodrug vesicles
reactive oxygen species
triple-negative breast cancer
Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1655-1662
作者:
Dong, Xin-yue
;
Lang, Tian-qun
;
Yin, Qi
;
Zhang, Peng-cheng
;
Li, Ya-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
pH-sensitive polymer
co-delivery
micelle
docetaxel
silibinin
breast cancer
mouse breast cancer cell line 4T1
metastasis
6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib
期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 12, 页码: 5453-5465
作者:
Liu, Yanning
;
Lou, Guohua
;
Norton, John T.
;
Wang, Chen
;
Kandela, Irawati
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
MEAN
HCC therapeutic
combination treatment
C-MYC inhibition
Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel
期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 23, 页码: 6499-6512
作者:
Xie, Rui
;
Xu, Jingyu
;
Xiao, Yufeng
;
Wu, Jilin
;
Wan, Hanxing
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2019/01/08
Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 44
作者:
Zhao, Pengfei
;
Yin, Weimin
;
Wu, Aihua
;
Tang, Yisi
;
Wang, Jinyu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
albumin nanoparticles
combination therapy
mannose receptors
multidrug resistance
SPARC
Dihydroartemisinin selectively inhibits PDGFR alpha-positive ovarian cancer growth and metastasis through inducing degradation of PDGFR alpha protein
期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:
Li, Xiaoguang
;
Ba, Qian
;
Liu, Yanling
;
Yue, Qingxi
;
Chen, Peizhan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Dihydroartemisinin
Epithelial-mesenchymal transition
metastasis
ovarian cancer
PDGFR alpha
Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors
期刊论文
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:
Hu, Xiuqin
;
Wang, Disha
;
Tong, Yi
;
Tong, Linjiang
;
Wang, Xia
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
EGFR
tyrosine kinase inhibitors
anilinopyrtmidine
glycosides
carbohydrate-based drugs
PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells
期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266
作者:
Li, Jiangmei
;
Gao, Zhen
;
Zhao, Dan
;
Zhang, Lunfeng
;
Qiao, Xinhua
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:
Chen, Lingfeng
;
Fu, Weitao
;
Feng, Chen
;
Qu, Rong
;
Tong, Linjiang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
Epidermal growth factor receptor
Tyrosine kinase inhibitors
Non-small cell lung cancer
T790M
Mutant-selective
Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:
Chen, Wen-hua
;
Song, Shan-shan
;
Qi, Ming-hui
;
Huan, Xia-juan
;
Wang, Ying-qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
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